Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.49 |
| ▸ | NPC1 | O15118 | 3/20 | 0.49 |
| ▸ | RAB9A | P51151 | 3/20 | 0.49 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.48 |
| ▸ | MEN1 | O00255 | 3/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.47 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.47 |
| ▸ | PSMD14 | O00487 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | BLM | P54132 | 1/20 | 0.47 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.47 |
| ▸ | GUSB | P08236 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28574866 | 0.84 | HDAC6 (0.61) | ALDH1A1SMN1; SMN2NPC1RAB9AKMT2A | |
| SCHEMBL28574645 | 0.84 | HDAC6 (0.61) | ALDH1A1SMN1; SMN2NPC1RAB9AHDAC1 | |
| SCHEMBL28573287 | 0.84 | PIK3CD (0.60) | SMN1; SMN2NPC1RAB9AHDAC1KMT2A | |
| SCHEMBL28573286 | 0.84 | PIK3CD (0.51) | ALDH1A1SMN1; SMN2NPC1RAB9AHDAC1 | |
| SCHEMBL21346519 | 0.83 | SMN1; SMN2 (0.60) | ALDH1A1SMN1; SMN2NPC1RAB9AKMT2A | |
| SCHEMBL28575615 | 0.82 | PIK3CD (0.52) | ALDH1A1SMN1; SMN2NPC1RAB9AHDAC1 | |
| SCHEMBL13105216 | 0.76 | KDM4E (0.65) | ALDH1A1SMN1; SMN2NPC1RAB9AHDAC1 | |
| SCHEMBL15078645 | 0.74 | ALDH1A1 (0.67) | ALDH1A1SMN1; SMN2NPC1RAB9AHDAC1 | |
| SCHEMBL14463321 | 0.73 | ACHE (0.68) | SMN1; SMN2NPC1RAB9AKMT2AMEN1 | |
| SCHEMBL10000252 | 0.73 | ALDH1A1 (0.72) | ALDH1A1SMN1; SMN2NPC1RAB9AHDAC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112981436-B | Method for synthesizing 2-amino-1, 3, 4-thiadiazole derivative through electrochemical oxidation | 昆明学院 | 2022-02-01 | — | — | CN | claimed |
| CN-112981436-A | Method for synthesizing 2-amino-1, 3, 4-thiadiazole derivative through electrochemical oxidation | 昆明学院 | 2021-06-18 | — | — | CN | claimed |
| CN-112981436-B | Method for synthesizing 2-amino-1, 3, 4-thiadiazole derivative through electrochemical oxidation | 昆明学院 | 2022-02-01 | — | — | CN | disclosed |
| CN-112981436-A | Method for synthesizing 2-amino-1, 3, 4-thiadiazole derivative through electrochemical oxidation | 昆明学院 | 2021-06-18 | — | — | CN | disclosed |