Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CD | O00329 | 1/20 | 0.51 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.51 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.49 |
| ▸ | HPGD | P15428 | 2/20 | 0.49 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | P2RY1 | P47900 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.46 |
| ▸ | NPC1 | O15118 | 2/20 | 0.46 |
| ▸ | RAB9A | P51151 | 2/20 | 0.46 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.45 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.45 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.45 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | GUSB | P08236 | 1/20 | 0.43 |
| ▸ | KIF11 | P52732 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28575615 | 0.87 | PIK3CD (0.52) | PIK3CDPIK3CAPIK3CBALDH1A1NPSR1 | |
| SCHEMBL28587308 | 0.85 | HDAC6 (0.60) | PIK3CDPIK3CAPIK3CBHPGDMEN1 | |
| SCHEMBL28578701 | 0.85 | PIK3CD (0.67) | PIK3CDPIK3CAPIK3CBALDH1A1HPGD | |
| SCHEMBL28569839 | 0.84 | ALDH1A1 (0.50) | PIK3CDPIK3CAPIK3CBALDH1A1HPGD | |
| SCHEMBL28574866 | 0.80 | HDAC6 (0.61) | PIK3CDPIK3CAPIK3CBALDH1A1HPGD | |
| SCHEMBL1981416 | 0.76 | HPGD (0.54) | HPGDMEN1KMT2AKIF11 | |
| SCHEMBL20214047 | 0.75 | HDAC1 (0.51) | PIK3CDPIK3CAPIK3CBALDH1A1HPGD | |
| SCHEMBL23610351 | 0.75 | ALOX5 (0.76) | ALDH1A1HPGDNPSR1MEN1KMT2A | |
| SCHEMBL5813654 | 0.74 | P2RY1 (0.47) | PIK3CDPIK3CAPIK3CBALDH1A1P2RY1 | |
| SCHEMBL28915208 | 0.74 | NPC1 (0.63) | PIK3CDPIK3CAPIK3CBALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112981436-B | Method for synthesizing 2-amino-1, 3, 4-thiadiazole derivative through electrochemical oxidation | 昆明学院 | 2022-02-01 | — | — | CN | claimed |
| CN-112981436-A | Method for synthesizing 2-amino-1, 3, 4-thiadiazole derivative through electrochemical oxidation | 昆明学院 | 2021-06-18 | — | — | CN | claimed |
| CN-112981436-B | Method for synthesizing 2-amino-1, 3, 4-thiadiazole derivative through electrochemical oxidation | 昆明学院 | 2022-02-01 | — | — | CN | disclosed |
| CN-112981436-A | Method for synthesizing 2-amino-1, 3, 4-thiadiazole derivative through electrochemical oxidation | 昆明学院 | 2021-06-18 | — | — | CN | disclosed |