Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATR | Q13535 | 2/20 | 0.34 |
| ▸ | ATRIP | Q8WXE1 | 1/20 | 0.34 |
| ▸ | VNN1 | O95497 | 2/20 | 0.31 |
| ▸ | PRMT5 | O14744 | 2/20 | 0.31 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.30 |
| ▸ | FEN1 | P39748 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23629194 | 1.00 | ATR (0.34) | ATRATRIPVNN1PRMT5ALOX5AP | |
| SCHEMBL24024047 | 0.90 | VNN1 (0.30) | VNN1 | |
| SCHEMBL23408450 | 0.86 | PIK3CD (0.35) | VNN1PRMT5ALOX5APFEN1 | |
| SCHEMBL23408498 | 0.81 | CNR2 (0.38) | VNN1PRMT5ALOX5APFEN1 | |
| SCHEMBL28589312 | 0.80 | UCHL1 (0.40) | — | |
| SCHEMBL22792091 | 0.75 | F2RL1 (0.32) | — | |
| SCHEMBL29968500 | 0.75 | CA12 (0.35) | VNN1PRMT5ALOX5APFEN1 | |
| SCHEMBL28582530 | 0.72 | VNN1 (0.35) | VNN1PRMT5ALOX5APFEN1 | |
| SCHEMBL28582531 | 0.72 | VNN1 (0.35) | VNN1PRMT5ALOX5APFEN1 | |
| SCHEMBL29967694 | 0.72 | VNN1 (0.35) | VNN1PRMT5ALOX5APFEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112654396-A | 5-morpholin-4-yl-pyrazolo [4,3-b ] pyridine derivatives | 默克专利股份公司 | 2021-04-13 | — | — | CN | disclosed |