SCHEMBL28573264

SCHEMBL28573264

CCC(C)(C)c1cc([N+](=O)[O-])c(O)c([N+](=O)[O-])c1[N+](=O)[O-]

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GPR35 Q9HC97 7/20 0.47
ALDH1A1 P00352 3/20 0.40
MEN1 O00255 2/20 0.40
KMT2A Q03164 2/20 0.40
TDP1 Q9NUW8 2/20 0.40
GALR3 O60755 1/20 0.40
HTT P42858 1/20 0.40
SMN1; SMN2 Q16637 1/20 0.40
L3MBTL1 Q9Y468 1/20 0.40
TSHR P16473 1/20 0.40
MAPT P10636 2/20 0.39
KDM4E B2RXH2 1/20 0.38
TTR P02766 1/20 0.38
CYP1A2 P05177 1/20 0.38
CYP2C9 P11712 1/20 0.38
HPGD P15428 1/20 0.38
ALOX15 P16050 1/20 0.38
ALOX12 P18054 1/20 0.38
MAPK1 P28482 1/20 0.38
RECQL P46063 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28570533 0.77 GPR35 (0.68) GPR35ALDH1A1MEN1KMT2ATDP1
SCHEMBL17378837 0.74 GPR35 (0.39) GPR35ALDH1A1MEN1KMT2ATDP1
SCHEMBL6498479 0.72 GPR35 (0.51) GPR35ALDH1A1MEN1KMT2ATDP1
SCHEMBL18467780 0.72 SMN1; SMN2 (0.44) GPR35ALDH1A1MEN1KMT2ATDP1
Methyl Alcohol SCHEMBL29086960 0.72 GPR35 (0.59) GPR35ALDH1A1MEN1KMT2ATDP1
SCHEMBL4973651 0.72 GPR35 (0.55) GPR35ALDH1A1MEN1KMT2ATDP1
SCHEMBL8653042 0.71 ALDH1A1 (0.38) GPR35ALDH1A1MEN1KMT2ATDP1
SCHEMBL69964 0.71 GPR35 (0.59) GPR35ALDH1A1MEN1KMT2ATDP1
SCHEMBL1479104 0.71 GPR35 (0.59) GPR35ALDH1A1MEN1KMT2ATDP1
SCHEMBL10813721 0.71 TSHR (0.39) ALDH1A1MEN1KMT2ATDP1GALR3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-112661649-B 2,6-dinitro-4-tert-amylphenol and preparation method thereof 宁波龙欣精细化工有限公司 2023-01-10 CN disclosed
CN-112661649-A 2, 6-dinitro-4-tert-amylphenol and preparation method thereof 宁波龙欣精细化工有限公司 2021-04-16 CN disclosed