SCHEMBL28570735

SCHEMBL28570735

CC(C)C(Cc1ccccc1)(C(=O)Oc1ccccc1)C(=O)Oc1ccccc1

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ELANE P08246 6/20 0.41
ATM Q13315 1/20 0.41
L3MBTL1 Q9Y468 1/20 0.41
NPC1 O15118 1/20 0.40
RAB9A P51151 1/20 0.40
TSHR P16473 1/20 0.40
TRPA1 O75762 1/20 0.40
SMN1; SMN2 Q16637 1/20 0.40
HIF1A Q16665 1/20 0.40
KCNH2 Q12809 2/20 0.39
OPRM1 P35372 2/20 0.39
OPRD1 P41143 2/20 0.39
MRGPRX2 Q96LB1 1/20 0.39
CHRM3 P20309 1/20 0.39
HRH2 P25021 1/20 0.39
HTR2A P28223 1/20 0.39
ADRA1A P35348 1/20 0.39
OPRK1 P41145 1/20 0.39
ALDH1A1 P00352 1/20 0.39
RECQL P46063 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6740786 0.81 ALDH1A1 (0.56) L3MBTL1TSHRSMN1; SMN2KCNH2OPRM1
SCHEMBL29220119 0.78 MAPT (0.45) ELANEATML3MBTL1NPC1RAB9A
SCHEMBL28553144 0.78 PTPN1 (0.41) ELANEATML3MBTL1NPC1RAB9A
SCHEMBL28396913 0.78 ELANE (0.47) ELANEATML3MBTL1SMN1; SMN2HIF1A
SCHEMBL28003852 0.78 MMP8 (0.53) ELANEATML3MBTL1SMN1; SMN2HIF1A
SCHEMBL21269477 0.78 SMN1; SMN2 (0.50) NPC1RAB9ATSHRTRPA1SMN1; SMN2
SCHEMBL28875971 0.78 SMN1; SMN2 (0.50) NPC1RAB9ATSHRTRPA1SMN1; SMN2
SCHEMBL21269521 0.78 SMN1; SMN2 (0.50) NPC1RAB9ATSHRTRPA1SMN1; SMN2
SCHEMBL21269478 0.78 SMN1; SMN2 (0.50) NPC1RAB9ATSHRTRPA1SMN1; SMN2
SCHEMBL28315549 0.78 SMN1; SMN2 (0.50) NPC1RAB9ATSHRTRPA1SMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-109678996-B Catalyst component and catalyst system for olefin polymerization, prepolymerized catalyst system and olefin polymerization method 中国石油化工股份有限公司 2021-11-19 CN disclosed
CN-109678998-B Catalyst component and catalyst system for olefin polymerization, prepolymerized catalyst system and olefin polymerization method 中国石油化工股份有限公司 2021-11-19 CN disclosed
CN-109679006-B Catalyst component and catalyst system for olefin polymerization, prepolymerized catalyst system and olefin polymerization method 中国石油化工股份有限公司 2021-08-03 CN disclosed
CN-109679004-B Catalyst component and catalyst system for olefin polymerization, prepolymerized catalyst system and olefin polymerization method 中国石油化工股份有限公司 2021-05-11 CN disclosed