Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.56 |
| ▸ | MMP8 | P22894 | 2/20 | 0.56 |
| ▸ | RECQL | P46063 | 1/20 | 0.56 |
| ▸ | PIN1 | Q13526 | 2/20 | 0.47 |
| ▸ | LMNA | P02545 | 3/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.43 |
| ▸ | POLB | P06746 | 2/20 | 0.43 |
| ▸ | PPID | Q08752 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.42 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.42 |
| ▸ | OPRD1 | P41143 | 2/20 | 0.42 |
| ▸ | MRGPRX2 | Q96LB1 | 1/20 | 0.42 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.42 |
| ▸ | HRH2 | P25021 | 1/20 | 0.42 |
| ▸ | HTR2A | P28223 | 1/20 | 0.42 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.42 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28260493 | 0.86 | ALDH1A1 (0.55) | ALDH1A1MMP8RECQLPIN1LMNA | |
| SCHEMBL6741847 | 0.85 | ALDH1A1 (0.51) | ALDH1A1MMP8RECQLPIN1LMNA | |
| SCHEMBL28556726 | 0.85 | TSHR (0.49) | ALDH1A1MMP8RECQLLMNAL3MBTL1 | |
| SCHEMBL6741299 | 0.84 | CYP3A4 (0.54) | ALDH1A1MMP8RECQLLMNASMN1; SMN2 | |
| SCHEMBL28261808 | 0.82 | ALDH1A1 (0.55) | ALDH1A1MMP8RECQLPIN1LMNA | |
| SCHEMBL11732965 | 0.82 | ALDH1A1 (0.39) | ALDH1A1MMP8RECQLLMNAHTR2A | |
| Malonic Acid SCHEMBL6829250 | 0.82 | MAPT (0.43) | ALDH1A1MMP8RECQLLMNASMN1; SMN2 | |
| SCHEMBL28570735 | 0.81 | ELANE (0.41) | ALDH1A1MMP8RECQLSMN1; SMN2L3MBTL1 | |
| SCHEMBL19745438 | 0.80 | MMP8 (0.46) | ALDH1A1MMP8RECQLPIN1LMNA | |
| SCHEMBL4419400 | 0.80 | ALDH1A1 (0.62) | ALDH1A1MMP8RECQLPIN1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1042372-B1 | COMPONENTS AND CATALYSTS FOR THE POLYMERIZATION OF OLEFINS | BASELL POLIOLEFINE SPA (IT) | 2004-07-14 | — | — | EP | disclosed |
| US-6699814-B2 | CATALYST COMPRISING PRODUCT OF REACTION BETWEEN SOLID CATALYST COMPONENT COMPRISING MAGNESIUM, TITANIUM, HALOGEN AND HETEROATOM CONTAINING MALONATE, ALKYLALUMINUM COMPOUND AND, OPTIONALLY, ONE OR MORE ELECTRON-DONOR COMPOUNDS | BASELL POLIOLEFINE ITALIA S.P.A. (IT) | 2004-03-02 | — | — | US | disclosed |
| US-6689850-B2 | Process for the polymerization of olefins | BASELL POLIOLEFINE ITALIA S.P.A. (IT) | 2004-02-10 | — | — | US | disclosed |
| US-6605562-B1 | Comprising TiCl4, MgCl2 and an electron donor compound selected from heteroatom containing esters of malonic acids; heteroatoms are preferably selected from F, Cl, Br, and Si | BASELL POLIOLEFINE ITALIA S.P.A. (IT) | 2003-08-12 | — | — | US | disclosed |