Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 1/20 | 0.56 |
| ▸ | CA1 | P00915 | 1/20 | 0.56 |
| ▸ | CA2 | P00918 | 1/20 | 0.56 |
| ▸ | CA7 | P43166 | 1/20 | 0.56 |
| ▸ | CA9 | Q16790 | 1/20 | 0.56 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.56 |
| ▸ | CYP1B1 | Q16678 | 8/20 | 0.54 |
| ▸ | CYP1A1 | P04798 | 7/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 7/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.48 |
| ▸ | CYP2E1 | P05181 | 1/20 | 0.48 |
| ▸ | CYP2C8 | P10632 | 1/20 | 0.48 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.48 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.48 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.48 |
| ▸ | CYP4B1 | P13584 | 1/20 | 0.48 |
| ▸ | CYP2B6 | P20813 | 1/20 | 0.48 |
| ▸ | CYP3A5 | P20815 | 1/20 | 0.48 |
| ▸ | CYP2A7 | P20853 | 1/20 | 0.48 |
| ▸ | CYP3A7 | P24462 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1547455 | 0.81 | CA12 (0.58) | CA12CA1CA2CA7CA9 | |
| SCHEMBL8589458 | 0.79 | CA12 (0.56) | CA12CA1CA2CA7CA9 | |
| SCHEMBL20663360 | 0.79 | ACHE (0.56) | CYP1A2CYP3A4CYP2C9CYP2C19ALDH1A1 | |
| SCHEMBL8589460 | 0.79 | CA12 (0.56) | CA12CA1CA2CA7CA9 | |
| SCHEMBL14468510 | 0.79 | GAA (0.41) | CA12CA1CA2CA7CA9 | |
| SCHEMBL10279315 | 0.79 | CA12 (0.56) | CA12CA1CA2CA7CA9 | |
| SCHEMBL147963 | 0.79 | CYP1B1 (0.59) | CA12CA1CA2CA7CA9 | |
| SCHEMBL26556937 | 0.78 | ALDH1A1 (0.38) | CA12CA1CA2CA7CA9 | |
| SCHEMBL222435 | 0.76 | CA12 (0.52) | CA12CA1CA2CA7CA9 | |
| SCHEMBL29825539 | 0.76 | CA12 (0.52) | CA12CA1CA2CA7CA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113024480-B | 4, 5-dihydro-5, 5-diphenyl isoxazole-3-formamide compound and application thereof | 河南省农业科学院植物保护研究所 | 2022-05-06 | — | — | CN | disclosed |
| CN-113024480-B | 4, 5-dihydro-5, 5-diphenyl isoxazole-3-formamide compound and application thereof | 河南省农业科学院植物保护研究所 | 2022-05-06 | — | — | CN | disclosed |
| CN-113024480-A | 4, 5-dihydro-5, 5-diphenyl isoxazole-3-formamide compound and application thereof | 河南省农业科学院植物保护研究所 | 2021-06-25 | — | — | CN | disclosed |