Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 2/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.45 |
| ▸ | HPGD | P15428 | 5/20 | 0.40 |
| ▸ | MAPT | P10636 | 5/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 5/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.40 |
| ▸ | POLB | P06746 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | USP2 | O75604 | 1/20 | 0.40 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | L3MBTL4 | Q8NA19 | 1/20 | 0.38 |
| ▸ | L3MBTL3 | Q96JM7 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13888877 | 0.79 | ACHE (0.56) | ACHEALDH1A1CYP3A4HPGDMAPT | |
| SCHEMBL12461104 | 0.79 | ACHE (0.56) | ACHEALDH1A1CYP3A4HPGDMAPT | |
| SCHEMBL28571690 | 0.79 | CA12 (0.56) | ALDH1A1CYP3A4HPGDMAPTCYP2C9 | |
| SCHEMBL26556937 | 0.78 | ALDH1A1 (0.38) | ACHEALDH1A1CYP3A4HPGDTDP1 | |
| SCHEMBL17133382 | 0.76 | ACHE (0.52) | ACHEALDH1A1CYP3A4HPGDMAPT | |
| SCHEMBL14930477 | 0.76 | MAPT (0.54) | ACHEALDH1A1CYP3A4MAPTL3MBTL1 | |
| SCHEMBL9938324 | 0.75 | ACHE (0.68) | ACHEALDH1A1CYP3A4HPGDMAPT | |
| SCHEMBL14926681 | 0.75 | MAPT (0.53) | ACHEALDH1A1CYP3A4MAPTL3MBTL1 | |
| SCHEMBL5252562 | 0.75 | ALDH1A1 (0.71) | ACHEALDH1A1CYP3A4HPGDMAPT | |
| SCHEMBL11317412 | 0.75 | ACHE (0.50) | ACHEALDH1A1CYP3A4HPGDMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023067322-A1 | TRICYCLIC GPR65 MODULATORS | Pathios Therapeutics Limited (GB) | 2023-04-27 | — | — | WO | disclosed |
| EP-2791137-B1 | PYRAZOLOPYRIDINE DERIVATIVES, PREPARATION PROCESS THEREFOR AND THERAPEUTIC USE THEREOF | SANOFI SA (FR) | 2019-01-23 | — | — | EP | disclosed |