SCHEMBL28572003

SCHEMBL28572003

[c]1ccc2c(c1)oc1cccc(-c3ccncc3)c12

nearest known ligand 0.36

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PIK3CD O00329 1/20 0.36
ALDH1A1 P00352 2/20 0.32
MAPT P10636 2/20 0.32
SMN1; SMN2 Q16637 2/20 0.32
MAPK1 P28482 2/20 0.32
HSD17B10 Q99714 2/20 0.32
NPC1 O15118 2/20 0.32
RAB9A P51151 2/20 0.32
KDM4E B2RXH2 1/20 0.32
LMNA P02545 1/20 0.32
HPGD P15428 1/20 0.32
BACE1 P56817 1/20 0.32
ATAD2 Q6PL18 2/20 0.31
KIT P10721 1/20 0.31
KDR P35968 1/20 0.31
FLT3 P36888 1/20 0.31
IMPDH2 P12268 2/20 0.31
TSHR P16473 1/20 0.31
HTT P42858 1/20 0.31
TNF P01375 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28581266 0.88 PIK3CD (0.36) PIK3CDALDH1A1MAPTSMN1; SMN2MAPK1
SCHEMBL21295920 0.86 BACE1 (0.33) ALDH1A1RAB9AKDM4EBACE1KIT
SCHEMBL28575154 0.85 CYP11B1 (0.39) ALDH1A1MAPTSMN1; SMN2HSD17B10NPC1
SCHEMBL21295971 0.81 ALOX5 (0.40) PIK3CDALDH1A1MAPTSMN1; SMN2MAPK1
SCHEMBL21295635 0.81 HSD17B10 (0.43) PIK3CDALDH1A1MAPTSMN1; SMN2MAPK1
SCHEMBL21295886 0.78 MAPK14 (0.38) ALDH1A1MAPTSMN1; SMN2MAPK1HSD17B10
SCHEMBL28567091 0.77 KDM4E (0.38) ALDH1A1MAPTSMN1; SMN2MAPK1HSD17B10
SCHEMBL2591759 0.74 ALDH1A1 (0.39) ALDH1A1MAPTSMN1; SMN2HSD17B10NPC1
SCHEMBL21295819 0.74 PIK3CD (0.35) PIK3CDALDH1A1MAPTSMN1; SMN2MAPK1
SCHEMBL21295687 0.74 ADORA3 (0.34) ALDH1A1MAPTSMN1; SMN2MAPK1HSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-109311844-B Triazine compound, method for producing same, and organic electroluminescent element containing same as constituent component 东曹株式会社 2021-07-20 CN disclosed
CN-112912372-A Cyclic azine compound, material for organic electroluminescent element, electron transport material for organic electroluminescent element, and organic electroluminescent element 东曹株式会社 2021-06-04 CN disclosed