Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK13 | O15264 | 5/20 | 0.52 |
| ▸ | MAPK12 | P53778 | 5/20 | 0.52 |
| ▸ | MAPK11 | Q15759 | 5/20 | 0.52 |
| ▸ | MAPK14 | Q16539 | 5/20 | 0.52 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | FLT1 | P17948 | 2/20 | 0.38 |
| ▸ | FLT4 | P35916 | 2/20 | 0.38 |
| ▸ | KDR | P35968 | 2/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | CASP1 | P29466 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | JAK2 | O60674 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2199850 | 0.94 | MAPK13 (0.52) | MAPK13MAPK12MAPK11MAPK14CYP3A4 | |
| SCHEMBL2855620 | 0.86 | MAPT (0.45) | MAPK13MAPK12MAPK11MAPK14ALDH1A1 | |
| SCHEMBL2857986 | 0.86 | ALDH1A1 (0.45) | MAPK13MAPK12MAPK11MAPK14ALDH1A1 | |
| SCHEMBL5174489 | 0.82 | CYP3A4 (0.50) | MAPK13MAPK12MAPK11MAPK14CYP3A4 | |
| SCHEMBL7035012 | 0.78 | CYP3A4 (0.48) | MAPK13MAPK12MAPK11MAPK14CYP3A4 | |
| SCHEMBL2198191 | 0.78 | SRD5A2 (0.47) | MAPK13MAPK12MAPK11MAPK14CYP3A4 | |
| SCHEMBL2196860 | 0.78 | MAPK13 (0.46) | MAPK13MAPK12MAPK11MAPK14CYP3A4 | |
| SCHEMBL2200547 | 0.78 | KMT2A (0.50) | MAPK13MAPK12MAPK11MAPK14ALDH1A1 | |
| SCHEMBL5172393 | 0.77 | MAPK13 (0.61) | MAPK13MAPK12MAPK11MAPK14CYP3A4 | |
| SCHEMBL7090488 | 0.77 | JAK2 (0.53) | CYP3A4ALDH1A1KDM4EMAPTHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101115728-B | Triazole substituted aminobenzophenone compounds | LEO PHARMA AS | 2012-12-19 | — | — | CN | disclosed |
| US-8293772-B2 | Triazole substituted aminobenzophenone compounds | LEO PHARMA A/S (DK) | 2012-10-23 | — | — | US | disclosed |
| EP-1828148-B1 | TRIAZOLE SUBSTITUTED AMINOBENZOPHENONE COMPOUNDS | LEO PHARMA AS (DK) | 2010-01-20 | — | — | EP | disclosed |
| CN-101115728-A | Triazole substituted aminobenzophenone compounds | LEO PHARMA AS (DK) | 2008-01-30 | — | — | CN | disclosed |
| US-20060128766-A1 | Triazole substituted aminobenzophenone compounds | LEO PHARMA A/S (DK) | 2006-06-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060128766-A1 | Triazole substituted aminobenzophenone compounds | NFKBIA, UACA, CYP1B1 | MAPK13 1436/4885MAPK12 1829/4885MAPK11 919/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.