SCHEMBL2861736

SCHEMBL2861736

CCCCSc1cc2c(cc1OCCCCCCCCCCCCCCCCCC[Si](Cl)(Cl)Cl)c1cc(SCCCC)c(SCCCC)cc1c1cc(SCCCC)c(SCCCC)cc21

nearest known ligand 0.35

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
▸ CNR2 P34972 1/20 0.35
▸ NPC1 O15118 1/20 0.34
▸ LMNA P02545 1/20 0.34
▸ PKM P14618 1/20 0.34
▸ HTT P42858 1/20 0.34
▸ RAB9A P51151 1/20 0.34
▸ PTGS2 P35354 4/20 0.33
▸ TLR8 Q9NR97 2/20 0.32
▸ AR P10275 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2860389 0.96 CNR2 (0.39) CNR2NPC1LMNAPKMHTT
SCHEMBL2859962 0.94 CNR2 (0.39) CNR2NPC1LMNAPKMHTT
SCHEMBL2859062 0.92 LMNA (0.36) CNR2NPC1LMNAPKMHTT
SCHEMBL2858934 0.87 CNR2 (0.35) CNR2NPC1LMNAPKMHTT
SCHEMBL2862084 0.86 TLR8 (0.37) LMNAPKMPTGS2TLR8
SCHEMBL2857308 0.86 AR (0.35) CNR2NPC1LMNAPKMHTT
SCHEMBL2852351 0.83 CNR2 (0.39) CNR2NPC1LMNAPKMHTT
SCHEMBL2859051 0.83 GPR84 (0.39) LMNAPTGS2
SCHEMBL2866418 0.82 CNR2 (0.38) CNR2LMNAHTTPTGS2
SCHEMBL2863568 0.81 TLR8 (0.40) LMNATLR8

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7758932-B2 Liquid crystal display device and display apparatus RICOH COMPANY, LTD. (JP) 2010-07-20 — — US disclosed
US-20080305280-A1 LIQUID CRYSTAL DISPLAY DEVICE AND DISPLAY APPARATUS RICOH COMPANY, LTD. 2008-12-11 — — US disclosed
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