SCHEMBL28573281

SCHEMBL28573281

CCCCCCC(CC)COc1ccccc1

nearest known ligand 0.56

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PRSS1 P07477 1/20 0.56
PRSS2 P07478 1/20 0.56
PRSS3 P35030 1/20 0.56
LTA4H P09960 2/20 0.49
ALDH1A1 P00352 4/20 0.48
CYP3A4 P08684 2/20 0.48
CA2 P00918 1/20 0.48
MAOA P21397 2/20 0.46
MLNR O43193 1/20 0.46
NR1I2 O75469 1/20 0.46
ESR1 P03372 1/20 0.46
NR3C1 P04150 1/20 0.46
PGR P06401 1/20 0.46
ADRB2 P07550 1/20 0.46
CHRM2 P08172 1/20 0.46
ADRB1 P08588 1/20 0.46
HTR1A P08908 1/20 0.46
ADRA2A P08913 1/20 0.46
ADORA3 P0DMS8 1/20 0.46
CHRM1 P11229 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7162660 1.00 PRSS1 (0.56) PRSS1PRSS2PRSS3LTA4HALDH1A1
SCHEMBL4913490 0.93 ALDH1A1 (0.54) PRSS1PRSS2PRSS3LTA4HALDH1A1
SCHEMBL13007357 0.93 LTA4H (0.51) PRSS1PRSS2PRSS3LTA4HALDH1A1
SCHEMBL17640341 0.93 LTA4H (0.51) PRSS1PRSS2PRSS3LTA4HALDH1A1
SCHEMBL20357959 0.87 PRSS1 (0.49) PRSS1PRSS2PRSS3ALDH1A1CYP3A4
SCHEMBL28029167 0.86 LMNA (0.50) LTA4HALDH1A1CYP3A4CA2MAOA
SCHEMBL11876955 0.85 LTA4H (0.47) PRSS1PRSS2PRSS3LTA4HALDH1A1
SCHEMBL1357035 0.84 ALDH1A1 (0.50) PRSS1PRSS2PRSS3ALDH1A1CYP3A4
SCHEMBL1356320 0.84 ALDH1A1 (0.50) PRSS1PRSS2PRSS3ALDH1A1CYP3A4
SCHEMBL28526946 0.82 LMNA (0.57) LTA4HMAOAADRB2ADRB1LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-112320766-B Preparation method and application of hollow mesoporous inorganic oxide nanosphere solid alkali 西南大学 2023-10-27 CN disclosed
CN-112320766-A Preparation method and application of hollow mesoporous inorganic oxide nanosphere solid base 西南大学 2021-02-05 CN disclosed