Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F2 | P00734 | 3/20 | 0.50 |
| ▸ | ST14 | Q9Y5Y6 | 1/20 | 0.50 |
| ▸ | F10 | P00742 | 14/20 | 0.43 |
| ▸ | SMYD3 | Q9H7B4 | 3/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.38 |
| ▸ | MAPK11 | Q15759 | 1/20 | 0.38 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28573730 | 1.00 | F2 (0.50) | F2ST14F10SMYD3MAPT | |
| SCHEMBL28580200 | 0.90 | F10 (0.42) | F2ST14F10SMYD3MAPT | |
| SCHEMBL25017867 | 0.90 | F2 (0.57) | F2ST14F10PRSS1 | |
| SCHEMBL28593712 | 0.89 | F10 (0.41) | F2ST14F10SMYD3MAPT | |
| SCHEMBL31689670 | 0.87 | F10 (0.45) | F2ST14F10SMYD3PRSS1 | |
| SCHEMBL28572149 | 0.87 | F10 (0.45) | F2ST14F10SMYD3PRSS1 | |
| SCHEMBL28572148 | 0.87 | F10 (0.45) | F2ST14F10SMYD3PRSS1 | |
| SCHEMBL28573606 | 0.85 | SMYD3 (0.47) | F2ST14F10SMYD3PRSS1 | |
| SCHEMBL28573604 | 0.85 | SMYD3 (0.47) | F2ST14F10SMYD3PRSS1 | |
| SCHEMBL28579688 | 0.84 | F2 (0.48) | F2ST14F10SMYD3PRSS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112996529-A | Matriptase 2 inhibitor and application thereof | 迪斯克医药公司 | 2021-06-18 | — | — | CN | disclosed |