Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMYD3 | Q9H7B4 | 5/20 | 0.47 |
| ▸ | F10 | P00742 | 5/20 | 0.44 |
| ▸ | ST14 | Q9Y5Y6 | 3/20 | 0.41 |
| ▸ | PRSS1 | P07477 | 3/20 | 0.41 |
| ▸ | PRSS2 | P07478 | 2/20 | 0.41 |
| ▸ | PRSS3 | P35030 | 2/20 | 0.41 |
| ▸ | PLG | P00747 | 1/20 | 0.41 |
| ▸ | F2 | P00734 | 3/20 | 0.41 |
| ▸ | DRD4 | P21917 | 2/20 | 0.40 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.39 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.39 |
| ▸ | CCR8 | P51685 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | CCR3 | P51677 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28573606 | 1.00 | SMYD3 (0.47) | SMYD3F10ST14PRSS1PRSS2 | |
| SCHEMBL28578395 | 0.92 | F10 (0.48) | F10ST14PRSS1PRSS2PRSS3 | |
| SCHEMBL28578396 | 0.92 | F10 (0.48) | F10ST14PRSS1PRSS2PRSS3 | |
| SCHEMBL25017932 | 0.91 | F2 (0.49) | SMYD3F10ST14PRSS1PRSS2 | |
| SCHEMBL25016809 | 0.91 | F2 (0.49) | SMYD3F10ST14PRSS1PRSS2 | |
| SCHEMBL28573728 | 0.85 | F2 (0.50) | SMYD3F10ST14PRSS1F2 | |
| SCHEMBL28573730 | 0.85 | F2 (0.50) | SMYD3F10ST14PRSS1F2 | |
| SCHEMBL25016086 | 0.82 | F2 (0.48) | F10ST14PRSS1PRSS2PRSS3 | |
| SCHEMBL31689670 | 0.82 | F10 (0.45) | SMYD3F10ST14PRSS1PRSS2 | |
| SCHEMBL28575219 | 0.82 | F2 (0.48) | F10ST14PRSS1PRSS2PRSS3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112996529-A | Matriptase 2 inhibitor and application thereof | 迪斯克医药公司 | 2021-06-18 | — | — | CN | disclosed |