Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F10 | P00742 | 16/20 | 0.41 |
| ▸ | F2 | P00734 | 4/20 | 0.38 |
| ▸ | ST14 | Q9Y5Y6 | 1/20 | 0.38 |
| ▸ | PRSS1 | P07477 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | NOD2 | Q9HC29 | 1/20 | 0.35 |
| ▸ | NOD1 | Q9Y239 | 1/20 | 0.35 |
| ▸ | SMYD3 | Q9H7B4 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25016210 | 0.90 | F2 (0.44) | F10F2ST14PRSS1 | |
| SCHEMBL25016673 | 0.90 | F2 (0.44) | F10F2ST14PRSS1 | |
| SCHEMBL28573730 | 0.89 | F2 (0.50) | F10F2ST14PRSS1MAPT | |
| SCHEMBL28573728 | 0.89 | F2 (0.50) | F10F2ST14PRSS1MAPT | |
| SCHEMBL28580200 | 0.87 | F10 (0.42) | F10F2ST14PRSS1MAPT | |
| SCHEMBL28573606 | 0.80 | SMYD3 (0.47) | F10F2ST14PRSS1SMYD3 | |
| SCHEMBL28573604 | 0.80 | SMYD3 (0.47) | F10F2ST14PRSS1SMYD3 | |
| SCHEMBL21822135 | 0.79 | ITGB3 (0.40) | F10F2PRSS1 | |
| SCHEMBL25017867 | 0.79 | F2 (0.57) | F10F2ST14PRSS1 | |
| SCHEMBL25017315 | 0.78 | F10 (0.45) | F10F2PRSS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112996529-A | Matriptase 2 inhibitor and application thereof | 迪斯克医药公司 | 2021-06-18 | — | — | CN | disclosed |