SCHEMBL28367117

SCHEMBL28367117

CC(C)(C)c1ccc2c(c1)c1cc(C(C)(C)C)ccc1n2-c1ccccc1-c1ccc(C#N)cc1

nearest known ligand 0.49

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KIF11 P52732 2/20 0.49
KDM1A O60341 1/20 0.36
RORC P51449 2/20 0.36
DNMT1 P26358 3/20 0.36
SLC22A12 Q96S37 1/20 0.35
PGR P06401 2/20 0.35
FNTA P49354 1/20 0.35
FNTB P49356 1/20 0.35
PGGT1B P53609 1/20 0.35
CNR1 P21554 1/20 0.35
CNR2 P34972 1/20 0.35
CYP19A1 P11511 1/20 0.35
NPC1 O15118 1/20 0.34
ALDH1A1 P00352 1/20 0.34
PLA2G1B P04054 1/20 0.34
NFKB1 P19838 1/20 0.34
CASP3 P42574 1/20 0.34
RAB9A P51151 1/20 0.34
NFKB2 Q00653 1/20 0.34
RELA Q04206 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28367813 0.89 KIF11 (0.48) KIF11KDM1AALDH1A1PDK2AR
SCHEMBL28574243 0.88 KIF11 (0.50) KIF11KDM1APGRFNTAFNTB
SCHEMBL28570002 0.88 ADRA2C (0.40) KIF11DNMT1SLC22A12CNR1CNR2
SCHEMBL24002727 0.87 KIF11 (0.51) KIF11KDM1ARORCPGRFNTA
SCHEMBL18361182 0.87 KIF11 (0.47) KIF11KDM1APGRFNTAFNTB
SCHEMBL26533147 0.86 KIF11 (0.42) KIF11KDM1APGRFNTAFNTB
SCHEMBL28371565 0.86 RORC (0.36) KIF11RORCDNMT1PGRNPC1
SCHEMBL28367118 0.86 KIF11 (0.41) KIF11RORCDNMT1CNR1CNR2
SCHEMBL28371444 0.86 KIF11 (0.37) KIF11DNMT1FNTAFNTBPGGT1B
SCHEMBL28371604 0.86 KIF11 (0.40) KIF11DNMT1PGRALDH1A1PDK2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-112638874-A Benzonitrile derivative, light-emitting material, and light-emitting element using the same 国立大学法人九州大学 2021-04-09 CN disclosed
CN-110914378-A Composition for use in organic light emitting diodes 九州有机光材股份有限公司 2020-03-24 CN disclosed