Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 4/20 | 0.51 |
| ▸ | CA1 | P00915 | 4/20 | 0.51 |
| ▸ | CA2 | P00918 | 4/20 | 0.51 |
| ▸ | CA9 | Q16790 | 4/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | OGG1 | O15527 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | GSK3B | P49841 | 1/20 | 0.32 |
| ▸ | CES2 | O00748 | 1/20 | 0.32 |
| ▸ | CES1 | P23141 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4602946 | 0.72 | CA12 (0.51) | CA12CA1CA2CA9AKR1B1 | |
| SCHEMBL30211545 | 0.71 | CA12 (0.46) | CA12CA1CA2CA9SMN1; SMN2 | |
| SCHEMBL20709926 | 0.69 | KMT2A (0.47) | CA12CA1CA2CA9ALDH1A1 | |
| SCHEMBL4960220 | 0.67 | CA12 (0.42) | CA12CA1CA2CA9ALDH1A1 | |
| SCHEMBL1259804 | 0.66 | — | — | |
| SCHEMBL28125101 | 0.63 | — | — | |
| SCHEMBL1140165 | 0.63 | ALDH1A1 (0.49) | ALDH1A1SMN1; SMN2KMT2ALMNA | |
| SCHEMBL11503583 | 0.62 | AKR1B1 (0.50) | CA12CA1CA2CA9ALDH1A1 | |
| SCHEMBL3736615 | 0.61 | CA12 (0.41) | CA12CA1CA2CA9KMT2A | |
| SCHEMBL14689475 | 0.60 | TSPO (0.54) | SMN1; SMN2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112088157-B | Aryl-bipyridylamine derivatives as phosphatidylinositol phosphokinase inhibitors | 拉文纳制药公司 | 2023-12-26 | — | — | CN | disclosed |
| CN-112088157-A | Aryl-bipyridine amine derivatives as phosphoinositide kinase inhibitors | 拉文纳制药公司 | 2020-12-15 | — | — | CN | disclosed |