Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 12/20 | 0.58 |
| ▸ | RAB9A | P51151 | 12/20 | 0.58 |
| ▸ | SMN1; SMN2 | Q16637 | 9/20 | 0.58 |
| ▸ | KDM4E | B2RXH2 | 8/20 | 0.58 |
| ▸ | MAPT | P10636 | 7/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.58 |
| ▸ | HPGD | P15428 | 5/20 | 0.58 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.58 |
| ▸ | NFKB2 | Q00653 | 2/20 | 0.58 |
| ▸ | RELA | Q04206 | 2/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.51 |
| ▸ | MEN1 | O00255 | 4/20 | 0.51 |
| ▸ | GAA | P10253 | 2/20 | 0.48 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.48 |
| ▸ | APBA1 | Q02410 | 1/20 | 0.48 |
| ▸ | KDM1A | O60341 | 1/20 | 0.47 |
| ▸ | MECP2 | P51608 | 1/20 | 0.46 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.46 |
| ▸ | TP53 | P04637 | 3/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28572741 | 0.83 | RAB9A (0.57) | NPC1RAB9ASMN1; SMN2KDM4EMAPT | |
| SCHEMBL28592600 | 0.78 | NPC1 (0.60) | NPC1RAB9ASMN1; SMN2KDM4EMAPT | |
| SCHEMBL2491419 | 0.78 | NPC1 (0.72) | NPC1RAB9ASMN1; SMN2KDM4EMAPT | |
| SCHEMBL30597434 | 0.77 | NPC1 (0.60) | NPC1RAB9ASMN1; SMN2KDM4EMAPT | |
| SCHEMBL6404572 | 0.77 | NPC1 (0.60) | NPC1RAB9ASMN1; SMN2KDM4EMAPT | |
| SCHEMBL21612970 | 0.77 | NPC1 (0.82) | NPC1RAB9ASMN1; SMN2KDM4EMAPT | |
| SCHEMBL28587627 | 0.77 | RAB9A (0.49) | NPC1RAB9ASMN1; SMN2KDM4EMAPT | |
| SCHEMBL28914357 | 0.75 | NPC1 (0.68) | NPC1RAB9ASMN1; SMN2KDM4EMAPT | |
| SCHEMBL28586736 | 0.75 | NPC1 (0.68) | NPC1RAB9ASMN1; SMN2KDM4EMAPT | |
| SCHEMBL2268609 | 0.75 | NPC1 (0.78) | NPC1RAB9ASMN1; SMN2KDM4EMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112243436-A | Diamine compound and method for producing same | 东洋纺株式会社 | 2021-01-19 | — | — | CN | disclosed |