SCHEMBL28574544

SCHEMBL28574544

CC(C)(C)OC(=O)C(OC=O)C1CCC(N(OCc2ccccc2)S(=O)(=O)c2ccccc2)CN1

nearest known ligand 0.35

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
CCR5 P51681 11/20 0.35
ESR2 Q92731 3/20 0.34
ESR1 P03372 1/20 0.34
L3MBTL1 Q9Y468 2/20 0.34
NPSR1 Q6W5P4 1/20 0.33
CTSL P07711 1/20 0.33
LTA4H P09960 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28587250 0.92 CCR5 (0.39) CCR5
SCHEMBL28582343 0.81 MAPK1 (0.39) CCR5L3MBTL1
SCHEMBL28593131 0.79 MAPK1 (0.36) CCR5ESR2L3MBTL1
SCHEMBL28574786 0.78 KMT2A (0.36) L3MBTL1NPSR1CTSLLTA4H
SCHEMBL28571751 0.74 CCR5 (0.38) CCR5
SCHEMBL23668282 0.70 NR1H2 (0.42) CCR5
SCHEMBL28571752 0.69 CYP2D6 (0.38)
SCHEMBL28574162 0.68 NR1H2 (0.44) CCR5
SCHEMBL23668288 0.65 MAPK1 (0.43) CCR5L3MBTL1
SCHEMBL30362739 0.64 L3MBTL1 (0.43) L3MBTL1NPSR1CTSL

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-112930338-A Process for the preparation of amino acid derivatives 株式会社API 2021-06-08 CN disclosed