SCHEMBL28574162

SCHEMBL28574162

COC(=O)[C@@H]1CC[C@@H](N(OCc2ccccc2)S(=O)(=O)c2ccccc2)CN1C(=O)OC(C)(C)C

nearest known ligand 0.44

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
NR1H2 P55055 3/20 0.44
NR1H3 Q13133 3/20 0.44
KLK7 P49862 1/20 0.42
FKBP1A P62942 2/20 0.41
CCR5 P51681 4/20 0.41
MCL1 Q07820 3/20 0.40
PTPN1 P18031 2/20 0.40
STS P08842 1/20 0.40
MMP2 P08253 1/20 0.40
ANPEP P15144 1/20 0.40
KLK5 Q9Y337 1/20 0.40
JAK2 O60674 1/20 0.38
JAK1 P23458 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30695869 0.92 CCR5 (0.42) NR1H2NR1H3KLK7CCR5MCL1
SCHEMBL23668282 0.92 NR1H2 (0.42) NR1H2NR1H3KLK7CCR5MCL1
SCHEMBL23668279 0.83 CCR5 (0.43) KLK7CCR5MCL1
SCHEMBL28577303 0.79 MMP2 (0.46) FKBP1ACCR5MMP2ANPEP
SCHEMBL30695875 0.78 MAPK1 (0.41) CCR5MMP2ANPEP
SCHEMBL23632315 0.78 KLK7 (0.52) NR1H2NR1H3KLK7FKBP1AMCL1
SCHEMBL15287962 0.78 KLK7 (0.41) KLK7FKBP1AMCL1
SCHEMBL15347003 0.78 KLK7 (0.41) KLK7FKBP1AMCL1
SCHEMBL15347117 0.78 MEN1 (0.43) KLK7MCL1PTPN1JAK2JAK1
SCHEMBL20009192 0.78 KLK7 (0.42) KLK7FKBP1AJAK2JAK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3854786-B1 METHOD FOR PRODUCING AMINO ACID DERIVATIVES UBE CORP (JP) 2026-02-18 EP disclosed
US-12281074-B2 Method for producing amino acid derivatives UBE CORPORATION (JP) 2025-04-22 US disclosed
CN-119707784-A Process for preparing amino acid derivatives 株式会社API 2025-03-28 CN disclosed
US-12202800-B2 Method for producing amino acid derivatives API CORPORATION (JP) 2025-01-21 US disclosed
CN-112930338-B Process for preparing amino acid derivatives 株式会社API 2024-12-24 CN disclosed
US-20240150292-A1 METHOD FOR PRODUCING AMINO ACID DERIVATIVES API CORPORATION (JP) 2024-05-09 US disclosed
US-11897844-B2 Method for producing amino acid derivatives API CORPORATION (JP) 2024-02-13 US disclosed
US-20240002340-A1 METHOD FOR PRODUCING AMINO ACID DERIVATIVES API CORPORATION (JP) 2024-01-04 US disclosed
CN-112930338-A Process for the preparation of amino acid derivatives 株式会社API 2021-06-08 CN disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240150292-A1 METHOD FOR PRODUCING AMINO ACID DERIVATIVES PTGS2, PTGES, PTGS1 NR1H2 3651/4885NR1H3 3278/4885KLK7 3640/4885
US-12202800-B2 Method for producing amino acid derivatives GLO1, BCAT2, BCAT1 NR1H2 2980/4885NR1H3 2829/4885KLK7 2474/4885
US-20240002340-A1 METHOD FOR PRODUCING AMINO ACID DERIVATIVES GLO1, BCAT2, BCAT1 NR1H2 2980/4885NR1H3 2829/4885KLK7 2474/4885
US-11897844-B2 Method for producing amino acid derivatives PTGS2, PTGES, PTGES2 NR1H2 3824/4885NR1H3 3530/4885KLK7 3712/4885
US-12281074-B2 Method for producing amino acid derivatives PTGS2, PTGES, PTGES2 NR1H2 3824/4885NR1H3 3530/4885KLK7 3712/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.