SCHEMBL2857461

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL2857462	1.00	CA12 (0.55)	CA12CA7CA9CA14ATM
	SCHEMBL2863719	0.91	CA12 (0.45)	CA12CA7CA9CA14ATM
	SCHEMBL2863723	0.91	CA12 (0.45)	CA12CA7CA9CA14ATM
	SCHEMBL2855588	0.90	ITGA4 (0.57)	CA12CA7CA9CA14ATM
	SCHEMBL2855590	0.90	ITGA4 (0.57)	CA12CA7CA9CA14ATM
	SCHEMBL2852769	0.90	CA12 (0.44)	CA12CA7CA9CA14ATM
	SCHEMBL2852771	0.90	CA12 (0.44)	CA12CA7CA9CA14ATM
	SCHEMBL2861953	0.90	ITGA4 (0.50)	CA12CA7CA9CA14KMT2A
	SCHEMBL2861954	0.90	ITGA4 (0.50)	CA12CA7CA9CA14KMT2A
	SCHEMBL1825062	0.88	CA12 (0.54)	CA12CA7CA9CA14ATM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.