Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.55 |
| ▸ | LMNA | P02545 | 2/20 | 0.55 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.51 |
| ▸ | HPGD | P15428 | 1/20 | 0.50 |
| ▸ | RAB9A | P51151 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.49 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28571282 | 0.86 | ALDH1A1 (0.68) | MAPTLMNAALDH1A1HPGDRAB9A | |
| SCHEMBL28573979 | 0.86 | SMN1; SMN2 (0.58) | MAPTLMNAALDH1A1RAB9ASMN1; SMN2 | |
| SCHEMBL28571913 | 0.84 | TLR7 (0.48) | MAPTLMNADGAT1ALDH1A1HPGD | |
| SCHEMBL28566966 | 0.83 | MAPT (0.70) | MAPTLMNAALDH1A1RAB9ASMN1; SMN2 | |
| SCHEMBL28583712 | 0.82 | ALDH1A1 (0.52) | MAPTLMNAALDH1A1HPGDRAB9A | |
| SCHEMBL4786121 | 0.81 | DGAT1 (0.70) | MAPTLMNADGAT1HPGDMEN1 | |
| SCHEMBL4741529 | 0.81 | DGAT1 (0.70) | MAPTLMNADGAT1HPGDMEN1 | |
| SCHEMBL4786124 | 0.81 | DGAT1 (0.70) | MAPTLMNADGAT1HPGDMEN1 | |
| SCHEMBL28914765 | 0.78 | KMT2A (0.63) | MAPTLMNAALDH1A1RAB9ASMN1; SMN2 | |
| SCHEMBL28568876 | 0.78 | HTT (0.72) | MAPTLMNAALDH1A1RAB9ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112778156-B | Bishydrazide structure compound, preparation method and application thereof | 中国科学院上海药物研究所 | 2023-03-14 | — | — | CN | claimed |
| CN-112778156-A | Bishydrazide structure compound, preparation method and application thereof | 中国科学院上海药物研究所 | 2021-05-11 | — | — | CN | claimed |
| CN-112778156-B | Bishydrazide structure compound, preparation method and application thereof | 中国科学院上海药物研究所 | 2023-03-14 | — | — | CN | disclosed |
| CN-112778156-A | Bishydrazide structure compound, preparation method and application thereof | 中国科学院上海药物研究所 | 2021-05-11 | — | — | CN | disclosed |