Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DGAT1 | O75907 | 8/20 | 0.70 |
| ▸ | LMNA | P02545 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 1/20 | 0.51 |
| ▸ | CES2 | O00748 | 1/20 | 0.47 |
| ▸ | CES1 | P23141 | 1/20 | 0.47 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.46 |
| ▸ | KDM2B | Q8NHM5 | 2/20 | 0.45 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | MGLL | Q99685 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4786124 | 1.00 | DGAT1 (0.70) | DGAT1LMNAMAPTCES2CES1 | |
| SCHEMBL4786121 | 1.00 | DGAT1 (0.70) | DGAT1LMNAMAPTCES2CES1 | |
| SCHEMBL4893436 | 0.86 | DGAT1 (0.95) | DGAT1LMNA | |
| SCHEMBL5446047 | 0.86 | DGAT1 (0.95) | DGAT1LMNA | |
| SCHEMBL4885327 | 0.83 | DGAT1 (1.00) | DGAT1 | |
| SCHEMBL28575018 | 0.81 | MAPT (0.55) | DGAT1LMNAMAPTMEN1HPGD | |
| SCHEMBL1855141 | 0.80 | HSD11B1 (0.60) | LMNAMAPTCES2CES1SRD5A2 | |
| SCHEMBL6399371 | 0.79 | DGAT1 (0.59) | DGAT1LMNAMAPTMEN1KMT2A | |
| SCHEMBL6405464 | 0.79 | DGAT1 (0.59) | DGAT1LMNAMAPTMEN1KMT2A | |
| SCHEMBL6399369 | 0.79 | DGAT1 (0.59) | DGAT1LMNAMAPTMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008090357-A2 | N, N; -SUBSTITUTED PIPERAZINES BINDING TO MELANOCORTIN RECEPTOR | PALATIN TECHNOLOGIES, INC. (US) | 2008-07-31 | — | — | WO | disclosed |