Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 3/20 | 0.69 |
| ▸ | MAPT | P10636 | 7/20 | 0.66 |
| ▸ | GAA | P10253 | 3/20 | 0.66 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.64 |
| ▸ | RAB9A | P51151 | 3/20 | 0.64 |
| ▸ | NPC1 | O15118 | 2/20 | 0.64 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.61 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.61 |
| ▸ | POLB | P06746 | 1/20 | 0.61 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.59 |
| ▸ | MEN1 | O00255 | 3/20 | 0.59 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.59 |
| ▸ | NAMPT | P43490 | 1/20 | 0.58 |
| ▸ | LMNA | P02545 | 3/20 | 0.57 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.55 |
| ▸ | GFER | P55789 | 1/20 | 0.55 |
| ▸ | USP2 | O75604 | 1/20 | 0.54 |
| ▸ | AMY1A | P0DUB6 | 1/20 | 0.54 |
| ▸ | THRB | P10828 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28583306 | 0.89 | NPC1 (0.69) | ALOX5MAPTGAASMN1; SMN2RAB9A | |
| SCHEMBL28575303 | 0.88 | MAPT (0.66) | ALOX5MAPTGAASMN1; SMN2RAB9A | |
| SCHEMBL28575173 | 0.88 | MAPT (0.66) | ALOX5MAPTGAASMN1; SMN2RAB9A | |
| SCHEMBL28594556 | 0.88 | CSNK2A1 (0.67) | ALOX5MAPTGAASMN1; SMN2RAB9A | |
| SCHEMBL14085826 | 0.87 | KMT2A (0.74) | MAPTGAASMN1; SMN2RAB9ANPC1 | |
| SCHEMBL28579111 | 0.87 | MAPT (0.59) | ALOX5MAPTGAASMN1; SMN2RAB9A | |
| SCHEMBL28575126 | 0.87 | ALOX5 (0.64) | ALOX5MAPTGAASMN1; SMN2RAB9A | |
| SCHEMBL28583757 | 0.86 | ALOX5 (0.77) | ALOX5MAPTGAASMN1; SMN2RAB9A | |
| SCHEMBL28573059 | 0.86 | NAMPT (0.61) | ALOX5MAPTGAASMN1; SMN2RAB9A | |
| SCHEMBL28584177 | 0.83 | ALOX5 (0.69) | ALOX5MAPTGAASMN1; SMN2RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113004219-A | Thiazole ring-containing amide compound and preparation method and application thereof | 贵州大学 | 2021-06-22 | — | — | CN | disclosed |