Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.66 |
| ▸ | GAA | P10253 | 2/20 | 0.66 |
| ▸ | ALOX5 | P09917 | 7/20 | 0.65 |
| ▸ | MEN1 | O00255 | 4/20 | 0.65 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.65 |
| ▸ | VCP | P55072 | 2/20 | 0.65 |
| ▸ | DEGS1 | O15121 | 1/20 | 0.65 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.65 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.65 |
| ▸ | AMY1A | P0DUB6 | 1/20 | 0.65 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.65 |
| ▸ | TSHR | P16473 | 1/20 | 0.65 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.65 |
| ▸ | MAPKAPK2 | P49137 | 1/20 | 0.65 |
| ▸ | PIM3 | Q86V86 | 1/20 | 0.65 |
| ▸ | MINK1 | Q8N4C8 | 1/20 | 0.65 |
| ▸ | SPHK2 | Q9NRA0 | 1/20 | 0.65 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.65 |
| ▸ | SPHK1 | Q9NYA1 | 1/20 | 0.65 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.64 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28583306 | 0.89 | NPC1 (0.69) | MAPTGAAALOX5MEN1KMT2A | |
| SCHEMBL28575303 | 0.88 | MAPT (0.66) | MAPTGAAALOX5MEN1KMT2A | |
| SCHEMBL28575151 | 0.88 | ALOX5 (0.69) | MAPTGAAALOX5MEN1KMT2A | |
| SCHEMBL28594556 | 0.88 | CSNK2A1 (0.67) | MAPTGAAALOX5MEN1KMT2A | |
| SCHEMBL14085829 | 0.87 | MAPT (0.75) | MAPTGAAMEN1KMT2AALOX15 | |
| SCHEMBL28583387 | 0.87 | ALOX5 (0.67) | MAPTGAAALOX5MEN1KMT2A | |
| SCHEMBL28580584 | 0.86 | ABL1 (0.76) | MAPTGAAALOX5MEN1KMT2A | |
| SCHEMBL28572918 | 0.86 | ABL1 (0.63) | MAPTGAAMEN1KMT2AVCP | |
| SCHEMBL28579111 | 0.85 | MAPT (0.59) | MAPTGAAALOX5MEN1KMT2A | |
| SCHEMBL28575126 | 0.85 | ALOX5 (0.64) | MAPTGAAALOX5MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113004219-A | Thiazole ring-containing amide compound and preparation method and application thereof | 贵州大学 | 2021-06-22 | — | — | CN | disclosed |