Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 2/20 | 0.69 |
| ▸ | RAB9A | P51151 | 2/20 | 0.69 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.69 |
| ▸ | MAPT | P10636 | 6/20 | 0.67 |
| ▸ | GAA | P10253 | 4/20 | 0.67 |
| ▸ | AMY1A | P0DUB6 | 2/20 | 0.67 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.67 |
| ▸ | MEN1 | O00255 | 3/20 | 0.62 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.62 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.60 |
| ▸ | NAMPT | P43490 | 1/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.56 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.56 |
| ▸ | USP2 | O75604 | 1/20 | 0.56 |
| ▸ | LMNA | P02545 | 1/20 | 0.56 |
| ▸ | THRB | P10828 | 1/20 | 0.56 |
| ▸ | HPGD | P15428 | 1/20 | 0.56 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.56 |
| ▸ | TSHR | P16473 | 1/20 | 0.56 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28575173 | 0.89 | MAPT (0.66) | NPC1RAB9ASMN1; SMN2MAPTGAA | |
| SCHEMBL28575151 | 0.89 | ALOX5 (0.69) | NPC1RAB9ASMN1; SMN2MAPTGAA | |
| SCHEMBL28575303 | 0.89 | MAPT (0.66) | NPC1RAB9ASMN1; SMN2MAPTGAA | |
| SCHEMBL28594556 | 0.89 | CSNK2A1 (0.67) | NPC1RAB9ASMN1; SMN2MAPTGAA | |
| SCHEMBL14085825 | 0.87 | HDAC1 (0.67) | NPC1RAB9ASMN1; SMN2MAPTGAA | |
| SCHEMBL28575126 | 0.86 | ALOX5 (0.64) | NPC1RAB9ASMN1; SMN2MAPTGAA | |
| SCHEMBL28575125 | 0.86 | MAPT (0.72) | NPC1RAB9ASMN1; SMN2MAPTGAA | |
| SCHEMBL17320209 | 0.84 | ALOX5 (0.85) | NPC1RAB9ASMN1; SMN2MAPTGAA | |
| SCHEMBL28583387 | 0.84 | ALOX5 (0.67) | NPC1RAB9ASMN1; SMN2MAPTGAA | |
| SCHEMBL28579111 | 0.84 | MAPT (0.59) | NPC1RAB9ASMN1; SMN2MAPTGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113004219-A | Thiazole ring-containing amide compound and preparation method and application thereof | 贵州大学 | 2021-06-22 | — | — | CN | disclosed |