SCHEMBL28575287

SCHEMBL28575287

NC(=O)Cc1ccc(S(=O)(=O)Nc2ccon2)cc1

nearest known ligand 0.57

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
SCN9A Q15858 1/20 0.41
KDM4E B2RXH2 2/20 0.41
HPGD P15428 1/20 0.41
MEN1 O00255 1/20 0.39
KMT2A Q03164 1/20 0.39
NPC1 O15118 1/20 0.39
RAB9A P51151 1/20 0.39
CA2 P00918 1/20 0.39
BRD4 O60885 1/20 0.39
ALDH1A1 P00352 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7093262 0.78 MAPT (0.59) KDM4EMEN1KMT2ARAB9AALDH1A1
SCHEMBL11661462 0.77 MAPT (0.57) KDM4EMEN1KMT2ARAB9AALDH1A1
SCHEMBL5564296 0.76 CA12 (0.54) HPGDMEN1KMT2AALDH1A1
SCHEMBL23440267 0.75 KDM4E (0.51) SCN9AKDM4EMEN1KMT2ACA2
SCHEMBL3477694 0.75 BRD4 (0.52) SCN9AKDM4EHPGDMEN1KMT2A
SCHEMBL2999261 0.74 KMT2A (0.64) KDM4EMEN1KMT2AALDH1A1
SCHEMBL28575293 0.74 ALDH1A1 (0.61) KDM4EMEN1KMT2ACA2ALDH1A1
SCHEMBL29441805 0.74
SCHEMBL7243110 0.73 MAPK1 (0.61) SCN9AMEN1KMT2ABRD4
SCHEMBL3154182 0.72 SCN3A (0.61) MEN1KMT2ACA2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-112812998-A New strain for degrading sulfamethoxazole and application thereof 宋金龙 2021-05-18 CN disclosed