SCHEMBL28575293

SCHEMBL28575293

CC(=O)Nc1ccc(S(=O)(=O)Nc2ccon2)cc1

nearest known ligand 0.61

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.61
KDM4E B2RXH2 2/20 0.61
L3MBTL1 Q9Y468 1/20 0.57
ATIC P31939 1/20 0.55
CA1 P00915 1/20 0.55
CA2 P00918 1/20 0.55
MMP1 P03956 1/20 0.55
MMP2 P08253 1/20 0.55
MMP9 P14780 1/20 0.55
MMP8 P22894 1/20 0.55
MMP13 P45452 1/20 0.55
MEN1 O00255 2/20 0.53
KMT2A Q03164 2/20 0.53
MAPK1 P28482 1/20 0.53
PKM P14618 1/20 0.53
GAA P10253 1/20 0.53
GFER P55789 1/20 0.53
AKT1 P31749 1/20 0.53
TDP1 Q9NUW8 1/20 0.53

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5564296 0.83 CA12 (0.54) ALDH1A1L3MBTL1MEN1KMT2AGAA
SCHEMBL1502536 0.80 ALDH1A1 (0.75) ALDH1A1MEN1KMT2AGFER
SCHEMBL6670019 0.76 ALDH1A1 (0.70) ALDH1A1MEN1KMT2AMAPK1GFER
SCHEMBL23440267 0.76 KDM4E (0.51) ALDH1A1KDM4ECA1CA2MMP1
SCHEMBL7093262 0.76 MAPT (0.59) ALDH1A1KDM4EMEN1KMT2A
SCHEMBL3477694 0.76 BRD4 (0.52) ALDH1A1KDM4EMEN1KMT2AMAPK1
SCHEMBL547543 0.75 KDM4E (1.00) ALDH1A1KDM4EL3MBTL1ATICMEN1
SCHEMBL171892 0.75
SCHEMBL11661462 0.75 MAPT (0.57) ALDH1A1KDM4EMEN1KMT2A
SCHEMBL3926249 0.74 KDM4E (0.66) ALDH1A1KDM4EL3MBTL1ATIC

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-112812998-B New strain for degrading sulfamethoxazole and application thereof 宋金龙 2023-07-07 CN disclosed
CN-112812998-B New strain for degrading sulfamethoxazole and application thereof 宋金龙 2023-07-07 CN disclosed
CN-112812998-A New strain for degrading sulfamethoxazole and application thereof 宋金龙 2021-05-18 CN disclosed