SCHEMBL28575352

SCHEMBL28575352

CCOC(O)(C(=O)CC)c1ccccc1

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
OPRM1 P35372 4/20 0.46
DRD3 P35462 2/20 0.46
DRD2 P14416 1/20 0.46
GRIN2D O15399 2/20 0.43
GRIN1 Q05586 2/20 0.43
GRIN2A Q12879 2/20 0.43
GRIN2B Q13224 2/20 0.43
GRIN2C Q14957 2/20 0.43
OPRD1 P41143 2/20 0.43
CACNA1F O60840 1/20 0.43
ABCB1 P08183 1/20 0.43
CYP2B6 P20813 1/20 0.43
DRD4 P21917 1/20 0.43
OPRK1 P41145 1/20 0.43
CACNA1D Q01668 1/20 0.43
KCNH2 Q12809 1/20 0.43
CACNA1S Q13698 1/20 0.43
CACNA1C Q13936 1/20 0.43
MRGPRX2 Q96LB1 1/20 0.43
SMN1; SMN2 Q16637 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28728476 0.86 SMN1; SMN2 (0.41) OPRM1DRD3DRD2GRIN2DGRIN1
SCHEMBL21644502 0.82 KMT2A (0.48) KCNH2SMN1; SMN2CYP3A4CYP2D6POLB
SCHEMBL251616 0.81 CES1 (0.50) SMN1; SMN2CYP3A4CYP2D6POLBKCNN4
Ether SCHEMBL6049600 0.77 CES1 (0.46) SMN1; SMN2CYP3A4CYP2D6POLBKCNN4
SCHEMBL30497944 0.75 OPRM1 (0.53) OPRM1DRD3DRD2GRIN2DGRIN1
SCHEMBL463621 0.75 OPRM1 (0.53) OPRM1DRD3DRD2GRIN2DGRIN1
SCHEMBL15562485 0.74 OPRM1 (0.49) OPRM1DRD3DRD2GRIN2DGRIN1
Phenol SCHEMBL28728595 0.74 OPRM1 (0.38) OPRM1DRD3DRD2GRIN2DGRIN1
Phenol SCHEMBL28728449 0.74 OPRM1 (0.38) OPRM1DRD3DRD2GRIN2DGRIN1
SCHEMBL12282314 0.73 OPRM1 (0.51) OPRM1DRD3DRD2GRIN2DGRIN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-113030324-A Method for detecting preservative hydroxy ethoxy phenyl butanone in infant care product 宁波中盛产品检测有限公司 2021-06-25 CN disclosed
CN-113030324-A Method for detecting preservative hydroxy ethoxy phenyl butanone in infant care product 宁波中盛产品检测有限公司 2021-06-25 CN disclosed