Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 | P35372 | 4/20 | 0.53 |
| ▸ | DRD3 | P35462 | 2/20 | 0.53 |
| ▸ | DRD2 | P14416 | 1/20 | 0.53 |
| ▸ | LMNA | P02545 | 1/20 | 0.51 |
| ▸ | HTT | P42858 | 1/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.51 |
| ▸ | GRIN2D | O15399 | 2/20 | 0.49 |
| ▸ | GRIN1 | Q05586 | 2/20 | 0.49 |
| ▸ | GRIN2A | Q12879 | 2/20 | 0.49 |
| ▸ | GRIN2B | Q13224 | 2/20 | 0.49 |
| ▸ | GRIN2C | Q14957 | 2/20 | 0.49 |
| ▸ | OPRD1 | P41143 | 2/20 | 0.49 |
| ▸ | CACNA1F | O60840 | 1/20 | 0.49 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.49 |
| ▸ | CYP2B6 | P20813 | 1/20 | 0.49 |
| ▸ | DRD4 | P21917 | 1/20 | 0.49 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.49 |
| ▸ | CACNA1D | Q01668 | 1/20 | 0.49 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.49 |
| ▸ | CACNA1S | Q13698 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29008162 | 0.83 | L3MBTL1 (0.53) | OPRM1DRD3DRD2LMNAHTT | |
| SCHEMBL30497944 | 0.83 | OPRM1 (0.53) | OPRM1DRD3DRD2LMNAHTT | |
| SCHEMBL10293315 | 0.81 | OPRM1 (0.51) | OPRM1DRD3DRD2LMNAHTT | |
| SCHEMBL13545191 | 0.81 | OPRM1 (0.51) | OPRM1DRD3DRD2LMNAHTT | |
| SCHEMBL12282314 | 0.81 | OPRM1 (0.51) | OPRM1DRD3DRD2LMNAHTT | |
| SCHEMBL5873291 | 0.80 | CYP2C9 (0.47) | OPRM1DRD3DRD2LMNAHTT | |
| SCHEMBL13828216 | 0.80 | OPRM1 (0.55) | OPRM1DRD3DRD2LMNAHTT | |
| SCHEMBL29921428 | 0.79 | OPRM1 (0.50) | OPRM1DRD3DRD2LMNAHTT | |
| SCHEMBL12883298 | 0.78 | HDAC3 (0.53) | OPRM1DRD3DRD2GRIN2DGRIN1 | |
| SCHEMBL270134 | 0.78 | MAPT (0.57) | OPRM1DRD3DRD2GRIN2DGRIN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120289457-A1 | PEPTIDE OLIGONUCLEOTIDE CONJUGATES | AVI BIOPHARMA, INC. (US) | 2012-11-15 | — | — | US | disclosed |
| US-20120065169-A1 | OLIGONUCLEOTIDE ANALOGUES HAVING MODIFIED INTERSUBUNIT LINKAGES AND/OR TERMINAL GROUPS | JPMORGAN CHASE BANK, N.A. AS ADMINISTRATIVE AGENT | 2012-03-15 | — | — | US | disclosed |
| CN-1280674-C | Photosensitive film for circuit formation and process for producing printed wiring board | HITACHI CHEMICAL CO LTD (JP) | 2006-10-18 | — | — | CN | disclosed |
| CN-1232884-C | Photoresisting agent composition | SHIPLEY INC (US) | 2005-12-21 | — | — | CN | disclosed |
| CN-1229692-C | Photo-corrosion-resisting agent composition | HIPPLY CO (US) | 2005-11-30 | — | — | CN | disclosed |
| CN-1500231-A | Photosensitive film for circuit formation and process for producing printed wiring board | 日立化成工业株式会社 | 2004-05-26 | — | — | CN | disclosed |
| CN-1428653-A | Photoresisting agent composition | SHIPLEY INC (US) | 2003-07-09 | — | — | CN | disclosed |
| CN-1427307-A | Photo-corrosion-resisting agent composition | HIPPLY CO (US) | 2003-07-02 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120065169-A1 | OLIGONUCLEOTIDE ANALOGUES HAVING MODIFIED INTERSUBUNIT LINKAGES AND/OR TERMINAL GROUPS | NSUN2, UPF1, RTCB | OPRM1 2325/4885DRD3 4414/4885DRD2 4736/4885 |
| US-20120289457-A1 | PEPTIDE OLIGONUCLEOTIDE CONJUGATES | SNRPE, SMN1; SMN2, UPF1 | OPRM1 3207/4885DRD3 4845/4885DRD2 4872/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.