Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SENP7 | Q9BQF6 | 2/20 | 0.60 |
| ▸ | ADORA1 | P30542 | 2/20 | 0.60 |
| ▸ | LMNA | P02545 | 1/20 | 0.57 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.56 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.56 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.55 |
| ▸ | NPSR1 | Q6W5P4 | 5/20 | 0.54 |
| ▸ | MEN1 | O00255 | 3/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.53 |
| ▸ | GAA | P10253 | 2/20 | 0.53 |
| ▸ | MAPT | P10636 | 2/20 | 0.53 |
| ▸ | HTT | P42858 | 2/20 | 0.53 |
| ▸ | CNR1 | P21554 | 1/20 | 0.53 |
| ▸ | CNR2 | P34972 | 1/20 | 0.53 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.53 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.53 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.53 |
| ▸ | CA12 | O43570 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28575234 | 0.92 | POLB (0.64) | SENP7ADORA1CHRM1MAPK1NPSR1 | |
| SCHEMBL28576814 | 0.92 | TP53 (0.59) | SENP7ADORA1LMNACHRM1L3MBTL1 | |
| SCHEMBL6116808 | 0.88 | CHRM1 (0.56) | ADORA1LMNACHRM1L3MBTL1MAPK1 | |
| SCHEMBL6116706 | 0.86 | L3MBTL1 (0.54) | ADORA1LMNACHRM1L3MBTL1MAPK1 | |
| SCHEMBL28583850 | 0.84 | SMN1; SMN2 (0.52) | SENP7LMNAMEN1KMT2AMAPT | |
| SCHEMBL28363339 | 0.84 | MAPT (0.55) | LMNAMAPK1MEN1KMT2AMAPT | |
| SCHEMBL28363587 | 0.83 | HDAC6 (0.65) | HDAC1HDAC6HDAC2 | |
| SCHEMBL18229445 | 0.82 | LMNA (0.71) | LMNACHRM1CNR1CNR2TP53 | |
| SCHEMBL6116507 | 0.82 | NPSR1 (0.57) | ADORA1LMNACHRM1L3MBTL1MAPK1 | |
| SCHEMBL28577420 | 0.81 | SLC22A12 (0.72) | ADORA1LMNAL3MBTL1MAPK1NPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113004187-B | Compound with function of inhibiting activity of organic anion transporter 1, preparation method and application | 沈阳药科大学 | 2022-09-20 | — | — | CN | disclosed |
| CN-113004187-A | Compound with function of inhibiting activity of organic anion transporter 1, preparation method and application | 沈阳药科大学 | 2021-06-22 | — | — | CN | disclosed |