Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 4/20 | 0.63 |
| ▸ | HTT | P42858 | 2/20 | 0.63 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.63 |
| ▸ | PLAU | P00749 | 2/20 | 0.59 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.57 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.57 |
| ▸ | MEN1 | O00255 | 2/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.57 |
| ▸ | FFAR4 | Q5NUL3 | 3/20 | 0.57 |
| ▸ | NPC1 | O15118 | 1/20 | 0.55 |
| ▸ | NR2F2 | P24468 | 1/20 | 0.55 |
| ▸ | RAB9A | P51151 | 1/20 | 0.55 |
| ▸ | KIF11 | P52732 | 1/20 | 0.54 |
| ▸ | TP53 | P04637 | 3/20 | 0.54 |
| ▸ | MAPT | P10636 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.52 |
| ▸ | PKM | P14618 | 1/20 | 0.52 |
| ▸ | TSHR | P16473 | 1/20 | 0.52 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.52 |
| ▸ | ERAP1 | Q9NZ08 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30292409 | 1.00 | LMNA (0.63) | LMNAHTTSMN1; SMN2PLAUALOX15 | |
| SCHEMBL28577596 | 0.88 | FFAR4 (0.53) | HTTSMN1; SMN2PLAUFFAR4KIF11 | |
| SCHEMBL28575423 | 0.86 | KIF11 (0.65) | LMNASMN1; SMN2PLAUMAPK1FFAR4 | |
| SCHEMBL28913958 | 0.84 | KIF11 (0.69) | SMN1; SMN2MAPK1FFAR4KIF11TP53 | |
| SCHEMBL6341473 | 0.84 | FFAR4 (0.56) | LMNAHTTSMN1; SMN2ALOX15MAPK1 | |
| SCHEMBL26530291 | 0.82 | GAA (0.68) | LMNAHTTSMN1; SMN2MAPK1MEN1 | |
| SCHEMBL28570098 | 0.79 | KIF11 (0.62) | SMN1; SMN2MAPK1FFAR4KIF11TP53 | |
| SCHEMBL26536730 | 0.79 | FFAR4 (0.60) | LMNASMN1; SMN2MAPK1FFAR4MAPT | |
| SCHEMBL28561814 | 0.79 | FFAR4 (0.61) | LMNAHTTSMN1; SMN2MEN1KMT2A | |
| SCHEMBL6795551 | 0.79 | LMNA (0.77) | LMNAHTTSMN1; SMN2ALOX15MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112876388-A | GPR120 agonist and preparation method and application thereof | 山东大学 | 2021-06-01 | — | — | CN | claimed |
| CN-112876388-B | GPR120 agonist and preparation method and application thereof | 山东大学 | 2023-03-31 | — | — | CN | disclosed |
| CN-112876388-A | GPR120 agonist and preparation method and application thereof | 山东大学 | 2021-06-01 | — | — | CN | disclosed |