Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KIF11 | P52732 | 1/20 | 0.65 |
| ▸ | PLAU | P00749 | 2/20 | 0.63 |
| ▸ | LMNA | P02545 | 1/20 | 0.62 |
| ▸ | GAA | P10253 | 1/20 | 0.62 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.62 |
| ▸ | TP53 | P04637 | 1/20 | 0.62 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.58 |
| ▸ | PGR | P06401 | 1/20 | 0.58 |
| ▸ | GSK3B | P49841 | 1/20 | 0.57 |
| ▸ | HDAC1 | Q13547 | 3/20 | 0.57 |
| ▸ | HDAC8 | Q9BY41 | 3/20 | 0.57 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.57 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.57 |
| ▸ | HDAC7 | Q8WUI4 | 2/20 | 0.57 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.57 |
| ▸ | HDAC10 | Q969S8 | 2/20 | 0.57 |
| ▸ | HDAC11 | Q96DB2 | 2/20 | 0.57 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.57 |
| ▸ | HDAC9 | Q9UKV0 | 2/20 | 0.57 |
| ▸ | HDAC5 | Q9UQL6 | 2/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26530291 | 0.96 | GAA (0.68) | KIF11LMNAGAAMAPK1TP53 | |
| SCHEMBL28913958 | 0.93 | KIF11 (0.69) | KIF11MAPK1TP53ALDH1A1GSK3B | |
| SCHEMBL32679643 | 0.88 | GAA (0.78) | PLAULMNAGAAMAPK1ALDH1A1 | |
| SCHEMBL28570098 | 0.87 | KIF11 (0.62) | KIF11MAPK1TP53ALDH1A1GSK3B | |
| SCHEMBL30292409 | 0.86 | LMNA (0.63) | KIF11PLAULMNAMAPK1TP53 | |
| SCHEMBL28575508 | 0.86 | LMNA (0.63) | KIF11PLAULMNAMAPK1TP53 | |
| SCHEMBL26536730 | 0.84 | FFAR4 (0.60) | LMNAGAAMAPK1HDAC1HDAC8 | |
| SCHEMBL6756075 | 0.84 | FFAR4 (0.68) | KIF11TP53ALDH1A1HDAC1HDAC8 | |
| SCHEMBL14601690 | 0.84 | FFAR4 (0.68) | KIF11TP53ALDH1A1HDAC1HDAC8 | |
| SCHEMBL28572870 | 0.84 | PGR (0.67) | KIF11LMNAMAPK1TP53PGR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112876388-A | GPR120 agonist and preparation method and application thereof | 山东大学 | 2021-06-01 | — | — | CN | claimed |
| CN-112876388-B | GPR120 agonist and preparation method and application thereof | 山东大学 | 2023-03-31 | — | — | CN | disclosed |
| CN-112876388-A | GPR120 agonist and preparation method and application thereof | 山东大学 | 2021-06-01 | — | — | CN | disclosed |