Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KEAP1 | Q14145 | 4/20 | 0.62 |
| ▸ | NFE2L2 | Q16236 | 4/20 | 0.62 |
| ▸ | MAPT | P10636 | 2/20 | 0.60 |
| ▸ | LMNA | P02545 | 3/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.59 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.59 |
| ▸ | TP53 | P04637 | 2/20 | 0.58 |
| ▸ | MEN1 | O00255 | 2/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.57 |
| ▸ | POLB | P06746 | 1/20 | 0.56 |
| ▸ | CNR1 | P21554 | 1/20 | 0.56 |
| ▸ | CNR2 | P34972 | 1/20 | 0.56 |
| ▸ | PPARG | P37231 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28575718 | 0.84 | KEAP1 (0.61) | KEAP1NFE2L2MAPTMEN1KMT2A | |
| SCHEMBL28563912 | 0.82 | LMNA (0.52) | KEAP1NFE2L2MAPTLMNAALDH1A1 | |
| SCHEMBL28561073 | 0.82 | KEAP1 (0.61) | KEAP1NFE2L2MAPTLMNAALDH1A1 | |
| SCHEMBL12533188 | 0.81 | KEAP1 (0.76) | KEAP1NFE2L2MAPTLMNAALDH1A1 | |
| SCHEMBL28567580 | 0.78 | POLB (0.59) | KEAP1NFE2L2MAPTALDH1A1TP53 | |
| SCHEMBL1629060 | 0.77 | KEAP1 (1.00) | KEAP1NFE2L2PPARG | |
| SCHEMBL7821400 | 0.77 | LMNA (0.72) | KEAP1NFE2L2LMNAALDH1A1NPSR1 | |
| SCHEMBL31159441 | 0.76 | LMNA (0.60) | KEAP1NFE2L2MAPTLMNAALDH1A1 | |
| SCHEMBL7003143 | 0.75 | KEAP1 (0.71) | KEAP1NFE2L2MAPTLMNAALDH1A1 | |
| SCHEMBL28564469 | 0.74 | LMNA (0.54) | KEAP1NFE2L2MAPTLMNAALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109336792-B | Synthesis method of 4-methyl-N-phenyl-N- (2-phenylallyl) benzene sulfonamide compound | 山东理工大学 | 2021-01-05 | — | — | CN | disclosed |