Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.54 |
| ▸ | MAPT | P10636 | 3/20 | 0.54 |
| ▸ | KEAP1 | Q14145 | 2/20 | 0.54 |
| ▸ | NFE2L2 | Q16236 | 2/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.51 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.49 |
| ▸ | USP2 | O75604 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | GLA | P06280 | 1/20 | 0.46 |
| ▸ | CNR1 | P21554 | 1/20 | 0.46 |
| ▸ | CNR2 | P34972 | 1/20 | 0.46 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.46 |
| ▸ | CA12 | O43570 | 1/20 | 0.46 |
| ▸ | CA9 | Q16790 | 1/20 | 0.46 |
| ▸ | PTGES | O14684 | 1/20 | 0.46 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | PPARG | P37231 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28561073 | 0.91 | KEAP1 (0.61) | LMNAMAPTKEAP1NFE2L2ALDH1A1 | |
| SCHEMBL28575718 | 0.89 | KEAP1 (0.61) | MAPTKEAP1NFE2L2KMT2AMEN1 | |
| SCHEMBL6204399 | 0.79 | KEAP1 (0.67) | MAPTKEAP1NFE2L2HCRTR2KMT2A | |
| SCHEMBL28567580 | 0.79 | POLB (0.59) | MAPTKEAP1NFE2L2ALDH1A1MAPK1 | |
| SCHEMBL699184 | 0.77 | KEAP1 (0.88) | KEAP1NFE2L2KMT2ACA12CA9 | |
| SCHEMBL14062173 | 0.76 | ALDH1A1 (0.52) | LMNAMAPTKEAP1NFE2L2ALDH1A1 | |
| SCHEMBL9819505 | 0.75 | ALDH1A1 (0.55) | LMNAKEAP1NFE2L2ALDH1A1MAPK1 | |
| SCHEMBL25347503 | 0.74 | TP53 (0.76) | LMNAMAPTALDH1A1KMT2ACA12 | |
| SCHEMBL7043992 | 0.74 | KEAP1 (0.59) | LMNAMAPTKEAP1NFE2L2ALDH1A1 | |
| SCHEMBL28575720 | 0.74 | KEAP1 (0.62) | LMNAMAPTKEAP1NFE2L2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109336792-B | Synthesis method of 4-methyl-N-phenyl-N- (2-phenylallyl) benzene sulfonamide compound | 山东理工大学 | 2021-01-05 | — | — | CN | disclosed |