Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 2/20 | 0.52 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.48 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.47 |
| ▸ | HTT | P42858 | 2/20 | 0.47 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | PLAU | P00749 | 1/20 | 0.46 |
| ▸ | ELANE | P08246 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11929784 | 0.82 | TP53 (0.48) | TP53POLBALDH1A1LMNASMN1; SMN2 | |
| SCHEMBL17237483 | 0.82 | TP53 (0.48) | TP53POLBALDH1A1LMNASMN1; SMN2 | |
| SCHEMBL5839153 | 0.81 | LMNA (0.60) | POLBALDH1A1LMNASMN1; SMN2HTT | |
| N Phthaloyl-L-Threonine SCHEMBL5424529 | 0.81 | TP53 (0.56) | TP53POLBALDH1A1LMNAHTT | |
| SCHEMBL1808319 | 0.79 | TP53 (0.45) | TP53POLBALDH1A1LMNASMN1; SMN2 | |
| SCHEMBL11929781 | 0.79 | TP53 (0.45) | TP53POLBALDH1A1LMNASMN1; SMN2 | |
| SCHEMBL1810083 | 0.79 | TP53 (0.45) | TP53POLBALDH1A1LMNASMN1; SMN2 | |
| SCHEMBL1811054 | 0.79 | TP53 (0.45) | TP53POLBALDH1A1LMNASMN1; SMN2 | |
| SCHEMBL1812413 | 0.79 | TP53 (0.45) | TP53POLBALDH1A1LMNASMN1; SMN2 | |
| SCHEMBL28221986 | 0.78 | POLB (0.48) | TP53POLBALDH1A1LMNASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112941043-B | Carbonyl reductase mutant and application thereof in preparation of chiral beta' -hydroxy-beta-amino acid ester | 中国科学院天津工业生物技术研究所 | 2021-09-10 | — | — | CN | disclosed |
| CN-112941043-B | Carbonyl reductase mutant and application thereof in preparation of chiral beta' -hydroxy-beta-amino acid ester | 中国科学院天津工业生物技术研究所 | 2021-09-10 | — | — | CN | disclosed |
| CN-112941043-A | Carbonyl reductase mutant and application thereof in preparation of chiral beta' -hydroxy-beta-amino acid ester | 中国科学院天津工业生物技术研究所 | 2021-06-11 | — | — | CN | disclosed |
| CN-112941043-A | Carbonyl reductase mutant and application thereof in preparation of chiral beta' -hydroxy-beta-amino acid ester | 中国科学院天津工业生物技术研究所 | 2021-06-11 | — | — | CN | disclosed |