Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.48 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | HTT | P42858 | 3/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.47 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.45 |
| ▸ | TP53 | P04637 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | TNF | P01375 | 2/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | PDE4A | P27815 | 1/20 | 0.44 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.44 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.44 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1184723 | 0.83 | ALDH1A1 (0.50) | LMNAHTTSMN1; SMN2ALDH1A1L3MBTL1 | |
| SCHEMBL5839153 | 0.82 | LMNA (0.60) | POLBLMNAHTTSMN1; SMN2ALOX15 | |
| SCHEMBL3625848 | 0.81 | ALDH1A1 (0.51) | LMNAHTTSMN1; SMN2ALDH1A1L3MBTL1 | |
| SCHEMBL1332360 | 0.81 | ALDH1A1 (0.51) | LMNAHTTSMN1; SMN2ALDH1A1L3MBTL1 | |
| SCHEMBL11590919 | 0.79 | ALDH1A1 (0.50) | LMNAHTTSMN1; SMN2ALDH1A1L3MBTL1 | |
| SCHEMBL11773628 | 0.79 | ALDH1A1 (0.55) | POLBHTTMAPK1ALDH1A1TP53 | |
| SCHEMBL7502491 | 0.78 | ALDH1A1 (0.50) | POLBHTTMAPK1ALDH1A1TP53 | |
| SCHEMBL17446693 | 0.78 | ALDH1A1 (0.50) | POLBHTTMAPK1ALDH1A1TP53 | |
| SCHEMBL28575796 | 0.78 | TP53 (0.52) | POLBLMNAHTTSMN1; SMN2ALOX15 | |
| SCHEMBL29260876 | 0.77 | POLB (0.47) | POLBLMNAHTTSMN1; SMN2ALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108299281-A | A kind of synthetic method of the deuterium-labeled a-amino acid of stable isotope | 上海化工研究院有限公司 | 2018-07-20 | — | — | CN | claimed |
| CN-108299281-A | A kind of synthetic method of the deuterium-labeled a-amino acid of stable isotope | 上海化工研究院有限公司 | 2018-07-20 | — | — | CN | disclosed |
| CN-108299281-A | A kind of synthetic method of the deuterium-labeled a-amino acid of stable isotope | 上海化工研究院有限公司 | 2018-07-20 | — | — | CN | disclosed |