SCHEMBL2857593

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL2858876	0.84	NTRK1 (0.58)	MAP2K4NTRK1FGFR2FGFR3FGFR1
	SCHEMBL2859865	0.82	MAP2K4 (0.51)	MAP2K4NTRK1HTR7AURKAMAPK1
	SCHEMBL4378603	0.82	MAPKAPK2 (0.45)	MAP2K4FGFR2FGFR3FGFR1AURKA
	SCHEMBL6759015	0.80	TAAR1 (0.54)	MAP2K4NTRK1FGFR2FGFR3FGFR1
	SCHEMBL2863237	0.77	CSNK1D (0.52)	MAP2K4NTRK1MAPK1
	SCHEMBL4151581	0.76	CHEK1 (0.56)	FGFR1AURKA
	SCHEMBL4151579	0.76	CHEK1 (0.56)	FGFR1AURKA
	SCHEMBL2868118	0.76	MAP2K4 (0.48)	MAP2K4NTRK1HTR7TDO2MAP2K7
	SCHEMBL13635746	0.75	CSNK1D (0.49)	MAP2K4NTRK1MAPK1
	SCHEMBL2857674	0.75	MAP2K4 (0.60)	MAP2K4MAPK1MAPKAPK3MAPK6MAP2K7

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.