SCHEMBL2858876

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL2862716	0.84	NTRK1 (0.55)	NTRK1MAP2K4TTKKDM4EALDH1A1
	SCHEMBL2857593	0.84	MAP2K4 (0.48)	NTRK1MAP2K4FGFR2FGFR3FGFR1
	SCHEMBL2862624	0.81	NTRK1 (0.55)	NTRK1MAP2K4TTKKDM4EALDH1A1
	SCHEMBL2863001	0.79	NTRK1 (0.56)	NTRK1MAP2K4TTKHPGDMAPK1
	SCHEMBL2864133	0.79	NTRK1 (0.53)	NTRK1MAP2K4TTKKDM4EALDH1A1
	SCHEMBL2864166	0.78	NTRK1 (0.49)	NTRK1MAP2K4TTKFYN
	SCHEMBL2864251	0.78	MAP2K4 (0.54)	NTRK1MAP2K4TTKKDM4EALDH1A1
	SCHEMBL2868827	0.76	MAP2K4 (0.54)	NTRK1MAP2K4TTK
	SCHEMBL2872610	0.76	DGAT2 (0.56)	NTRK1TTKKDM4EHPGDMAPK1
	SCHEMBL2870798	0.76	NTRK1 (0.52)	NTRK1ALDH1A1MAPK1PDE4B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.