Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 4/20 | 0.62 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.62 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.62 |
| ▸ | MEN1 | O00255 | 1/20 | 0.62 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.47 |
| ▸ | MAPT | P10636 | 5/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | ABCG2 | Q9UNQ0 | 5/20 | 0.44 |
| ▸ | HPGD | P15428 | 4/20 | 0.44 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.44 |
| ▸ | ABCC1 | P33527 | 3/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.40 |
| ▸ | HTT | P42858 | 3/20 | 0.40 |
| ▸ | ESR1 | P03372 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.40 |
| ▸ | CYP1A1 | P04798 | 2/20 | 0.40 |
| ▸ | CYP1B1 | Q16678 | 2/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
| ▸ | PDE5A | O76074 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28569270 | 1.00 | POLB (0.62) | POLBKMT2APTPN1MEN1ALDH1A1 | |
| SCHEMBL29950744 | 0.77 | PTPN1 (1.00) | POLBKMT2APTPN1MEN1ALDH1A1 | |
| SCHEMBL11869804 | 0.77 | POLB (0.59) | POLBKMT2APTPN1MEN1ALDH1A1 | |
| SCHEMBL11872015 | 0.77 | PTPN1 (1.00) | POLBKMT2APTPN1MEN1ALDH1A1 | |
| SCHEMBL21591554 | 0.76 | POLB (0.57) | POLBKMT2APTPN1MEN1ALDH1A1 | |
| SCHEMBL11549451 | 0.76 | POLB (0.57) | POLBKMT2APTPN1MEN1ALDH1A1 | |
| SCHEMBL11510369 | 0.76 | MAOB (0.59) | POLBKMT2APTPN1MEN1ALDH1A1 | |
| SCHEMBL22445015 | 0.75 | KMT2A (0.45) | POLBKMT2APTPN1MEN1ALDH1A1 | |
| SCHEMBL29693511 | 0.75 | POLB (0.63) | POLBKMT2APTPN1MEN1ALDH1A1 | |
| SCHEMBL18312297 | 0.75 | POLB (0.63) | POLBKMT2APTPN1MEN1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118406075-A | Silicon-containing polycyclic chromone skeleton compound, preparation method and application thereof | 遵义医科大学 | 2024-07-30 | — | — | CN | disclosed |
| CN-118255735-A | Preparation method of cyclopenta [ b ] chromone compound | 遵义医科大学 | 2024-06-28 | — | — | CN | disclosed |