Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.47 |
| ▸ | GPR35 | Q9HC97 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | PARP1 | P09874 | 1/20 | 0.39 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.38 |
| ▸ | CSNK2B | P67870 | 1/20 | 0.38 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.38 |
| ▸ | CSNK2A3 | Q8NEV1 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 2/20 | 0.38 |
| ▸ | S100A4 | P26447 | 2/20 | 0.38 |
| ▸ | POLB | P06746 | 2/20 | 0.37 |
| ▸ | DNA2 | P51530 | 1/20 | 0.37 |
| ▸ | CASP6 | P55212 | 1/20 | 0.37 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.37 |
| ▸ | MAOA | P21397 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29952203 | 0.79 | PTPN1 (0.55) | TDP1GPR35ALDH1A1POLBMAOA | |
| SCHEMBL7251833 | 0.76 | TDP1 (0.52) | TDP1GPR35ALDH1A1PARP1GAA | |
| SCHEMBL3274689 | 0.76 | TDP1 (0.52) | TDP1GPR35ALDH1A1PARP1GAA | |
| SCHEMBL28577211 | 0.73 | TTR (0.41) | POLBMAOAKMT2AMEN1 | |
| SCHEMBL28567067 | 0.73 | CES1 (0.42) | TDP1ALDH1A1POLBMAPTKMT2A | |
| SCHEMBL31290996 | 0.72 | GPR35 (0.52) | TDP1GPR35ALDH1A1PARP1GAA | |
| SCHEMBL3385902 | 0.70 | MAOA (0.57) | TDP1GPR35ALDH1A1CSNK2A2CSNK2B | |
| SCHEMBL28569270 | 0.69 | POLB (0.62) | ALDH1A1GAAPOLBMAPTKMT2A | |
| SCHEMBL31037935 | 0.69 | POLB (0.62) | ALDH1A1GAAPOLBMAPTKMT2A | |
| SCHEMBL6581379 | 0.69 | KMT2A (0.60) | TDP1GPR35ALDH1A1POLBMAOA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118255735-A | Preparation method of cyclopenta [ b ] chromone compound | 遵义医科大学 | 2024-06-28 | — | — | CN | disclosed |
| CN-113149948-B | Preparation method and application of 3-methylene cyclopentano [ b ] chromone compound | 遵义医科大学 | 2022-07-08 | — | — | CN | disclosed |
| CN-111732567-B | Chromone framework-containing polycyclic compound, and preparation method and application thereof | 遵义医科大学 | 2022-07-08 | — | — | CN | disclosed |
| CN-113149948-A | Preparation method and application of 3-methylene cyclopentano [ b ] chromone compound | 遵义医科大学 | 2021-07-23 | — | — | CN | disclosed |
| CN-111732567-A | Chromone framework-containing polycyclic compound, and preparation method and application thereof | 遵义医科大学 | 2020-10-02 | — | — | CN | disclosed |