SCHEMBL28577388

SCHEMBL28577388

CCCCCCC(c1nc(N)nc(N)n1)n1cc(C)nc1CC

nearest known ligand 0.32

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
TLR8 Q9NR97 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28559978 0.99 TLR8 (0.31) TLR8
SCHEMBL28575202 0.95 TLR8 (0.32) TLR8
SCHEMBL28566419 0.89
SCHEMBL28559984 0.84 HRH4 (0.30)
SCHEMBL28569887 0.81 DHFR (0.40) TLR8
SCHEMBL28563239 0.79 TLR8 (0.40) TLR8
SCHEMBL28569780 0.75 TSHR (0.39) TLR8
SCHEMBL28566839 0.75 HTR1A (0.38) TLR8
SCHEMBL28577363 0.74 TSHR (0.40) TLR8
SCHEMBL28569872 0.73 TLR7 (0.37) TLR8

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-112724596-A Curable composition and cured product 盛势达技研株式会社 2021-04-30 CN disclosed