Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR8 | Q9NR97 | 8/20 | 0.40 |
| ▸ | DHFR | P00374 | 1/20 | 0.38 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | HTR1A | P08908 | 1/20 | 0.35 |
| ▸ | HTR2A | P28223 | 1/20 | 0.35 |
| ▸ | HTR7 | P34969 | 1/20 | 0.35 |
| ▸ | HTR6 | P50406 | 1/20 | 0.35 |
| ▸ | HSD11B1 | P28845 | 2/20 | 0.35 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | CYP17A1 | P05093 | 1/20 | 0.34 |
| ▸ | GSK3B | P49841 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28569887 | 0.99 | DHFR (0.40) | TLR8DHFRPDE4BTSHRHTR1A | |
| SCHEMBL28566839 | 0.96 | HTR1A (0.38) | TLR8DHFRPDE4BTSHRHTR1A | |
| SCHEMBL28563228 | 0.91 | HTR1A (0.36) | TLR8DHFRTSHRHTR1AHTR2A | |
| SCHEMBL28560946 | 0.86 | ADORA2A (0.37) | TLR8DHFRHTR1AHTR2AHTR7 | |
| SCHEMBL28566843 | 0.82 | PDE4B (0.41) | TLR8DHFRPDE4BTSHRHTR1A | |
| SCHEMBL28913414 | 0.81 | PDE4B (0.40) | TLR8DHFRPDE4BTSHRHTR1A | |
| SCHEMBL28559978 | 0.80 | TLR8 (0.31) | TLR8 | |
| SCHEMBL28577388 | 0.79 | TLR8 (0.31) | TLR8 | |
| SCHEMBL28560025 | 0.79 | CYP17A1 (0.41) | TLR8DHFRPDE4BTSHRHTR1A | |
| SCHEMBL28575202 | 0.76 | TLR8 (0.32) | TLR8HTR1AHTR2AHTR7HTR6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112724596-A | Curable composition and cured product | 盛势达技研株式会社 | 2021-04-30 | — | — | CN | disclosed |