Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM2 | P08172 | 2/20 | 0.50 |
| ▸ | GAA | P10253 | 2/20 | 0.40 |
| ▸ | HTT | P42858 | 2/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.39 |
| ▸ | TOP2A | P11388 | 4/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.38 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.38 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.38 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.38 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.38 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.38 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.38 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.38 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.38 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.38 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.38 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.38 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28577447 | 0.73 | MAPT (0.59) | CHRM2GAAHTTHSD17B10CYP3A4 | |
| SCHEMBL29043490 | 0.71 | ADRA1A (0.61) | HSD17B10CYP3A4ADRA2AADRA2BADRA2C | |
| SCHEMBL16139561 | 0.70 | CHRM2 (0.97) | CHRM2HSD17B10CYP3A4PMP22ALDH1A1 | |
| SCHEMBL22652639 | 0.70 | CHRM2 (0.97) | CHRM2HSD17B10CYP3A4PMP22ALDH1A1 | |
| SCHEMBL23467818 | 0.70 | CHRM2 (0.97) | CHRM2HSD17B10CYP3A4PMP22ALDH1A1 | |
| SCHEMBL24267803 | 0.69 | CHRM2 (0.82) | CHRM2CYP3A4PMP22NPSR1 | |
| SCHEMBL20232445 | 0.69 | CHRM2 (0.82) | CHRM2CYP3A4PMP22NPSR1 | |
| SCHEMBL28975143 | 0.68 | MAPT (0.63) | CHRM2GAAHTTHSD17B10CYP3A4 | |
| SCHEMBL24714302 | 0.68 | ALDH1A1 (0.68) | GAAHTTALOX15ALDH1A1NPSR1 | |
| SCHEMBL335313 | 0.67 | CHRM2 (0.68) | CHRM2GAAHTTADRA1DADRA1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116082250-A | Novel method for preparing urapidil hydrochloride | 江苏润安制药有限公司 | 2023-05-09 | — | — | CN | disclosed |
| CN-109516960-B | Preparation method of urapidil hydrochloride | 河北一品制药股份有限公司 | 2021-07-02 | — | — | CN | disclosed |