Known targets — ChEMBL curated mechanism
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
The experimentally established mechanism targets of Phosphoric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 known ✓ | P35372 | 1/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.59 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.59 |
| ▸ | TP53 | P04637 | 1/20 | 0.57 |
| ▸ | FDPS | P14324 | 5/20 | 0.52 |
| ▸ | LAP3 | P28838 | 2/20 | 0.52 |
| ▸ | METAP1 | P53582 | 2/20 | 0.47 |
| ▸ | S1PR2 | O95136 | 5/20 | 0.46 |
| ▸ | S1PR1 | P21453 | 5/20 | 0.46 |
| ▸ | S1PR3 | Q99500 | 5/20 | 0.46 |
| ▸ | S1PR4 | O95977 | 4/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Tuaminoheptane SCHEMBL28624951 | 0.91 | OPRM1 (0.73) | ALDH1A1TDP1OPRM1TP53FDPS | |
| Phosphoric Acid SCHEMBL28584800 | 0.89 | OPRM1 (0.70) | ALDH1A1TDP1OPRM1TP53FDPS | |
| Phosphoric Acid SCHEMBL31513097 | 0.89 | OPRM1 (0.70) | ALDH1A1TDP1OPRM1TP53FDPS | |
| Phosphoric Acid SCHEMBL17746598 | 0.83 | METAP1 (0.58) | ALDH1A1TDP1OPRM1TP53FDPS | |
| SCHEMBL3854594 | 0.83 | OPRM1 (0.82) | ALDH1A1TDP1OPRM1TP53 | |
| SCHEMBL105432 | 0.83 | — | — | |
| SCHEMBL354351 | 0.83 | — | — | |
| SCHEMBL353779 | 0.83 | — | — | |
| Bicarbonate SCHEMBL6548682 | 0.81 | OPRM1 (0.64) | ALDH1A1TDP1OPRM1TP53 | |
| Hydrochloric Acid SCHEMBL8347529 | 0.80 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107753432-B | Liposome formulations and manufacture | 祖利控股有限公司 | 2021-01-05 | — | — | CN | disclosed |