Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATM | Q13315 | 1/20 | 0.47 |
| ▸ | APP | P05067 | 4/20 | 0.40 |
| ▸ | CTSS | P25774 | 3/20 | 0.40 |
| ▸ | CTSK | P43235 | 2/20 | 0.40 |
| ▸ | CTSL | P07711 | 1/20 | 0.40 |
| ▸ | CTSB | P07858 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 5/20 | 0.39 |
| ▸ | SYK | P43405 | 1/20 | 0.39 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.39 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | ACE | P12821 | 1/20 | 0.39 |
| ▸ | KLK5 | Q9Y337 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28588736 | 0.84 | ATM (0.44) | ATMAPPCTSSCTSKCTSL | |
| SCHEMBL28588738 | 0.84 | ATM (0.44) | ATMAPPCTSSCTSKCTSL | |
| SCHEMBL489490 | 0.81 | ATM (0.70) | ATMAPPCTSSCTSKCTSL | |
| SCHEMBL28583142 | 0.81 | ACE (0.54) | ATMAPPCTSSCTSKCTSL | |
| SCHEMBL29039971 | 0.81 | ACE (0.54) | ATMAPPCTSSCTSKCTSL | |
| SCHEMBL489489 | 0.81 | ATM (0.70) | ATMAPPCTSSCTSKCTSL | |
| SCHEMBL1519945 | 0.81 | ATM (0.70) | ATMAPPCTSSCTSKCTSL | |
| SCHEMBL740215 | 0.80 | ATM (0.55) | ATMAPPCTSSCTSKCTSL | |
| SCHEMBL740216 | 0.80 | ATM (0.55) | ATMAPPCTSSCTSKCTSL | |
| SCHEMBL6684772 | 0.79 | CA1 (0.49) | ATMCTSSCTSKCTSLCTSB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107709301-B | Pyrazole derivative or pharmacologically acceptable salt thereof | 橘生药品工业株式会社 | 2021-06-22 | — | — | CN | disclosed |