Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATM | Q13315 | 1/20 | 0.70 |
| ▸ | APP | P05067 | 4/20 | 0.57 |
| ▸ | CTSS | P25774 | 3/20 | 0.56 |
| ▸ | CTSK | P43235 | 2/20 | 0.56 |
| ▸ | CTSL | P07711 | 1/20 | 0.56 |
| ▸ | CTSB | P07858 | 1/20 | 0.56 |
| ▸ | ACE | P12821 | 1/20 | 0.54 |
| ▸ | KLK5 | Q9Y337 | 2/20 | 0.53 |
| ▸ | SYK | P43405 | 1/20 | 0.52 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1519945 | 1.00 | ATM (0.70) | ATMAPPCTSSCTSKCTSL | |
| SCHEMBL489490 | 1.00 | ATM (0.70) | ATMAPPCTSSCTSKCTSL | |
| SCHEMBL825492 | 0.92 | CTSS (0.61) | ATMAPPCTSSCTSKCTSL | |
| SCHEMBL3699140 | 0.92 | CTSS (0.61) | ATMAPPCTSSCTSKCTSL | |
| SCHEMBL28113260 | 0.90 | ATM (0.68) | ATMAPPCTSSCTSKCTSL | |
| SCHEMBL28113259 | 0.90 | ATM (0.68) | ATMAPPCTSSCTSKCTSL | |
| SCHEMBL2617274 | 0.89 | ATM (0.58) | ATMAPPCTSSCTSKCTSL | |
| SCHEMBL5888032 | 0.89 | ATM (0.58) | ATMAPPCTSSCTSKCTSL | |
| SCHEMBL17376003 | 0.89 | ATM (0.67) | ATMAPPCTSSCTSKCTSL | |
| SCHEMBL7239876 | 0.89 | ATM (0.67) | ATMAPPCTSSCTSKCTSL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 127 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116874803-A | Antibacterial dendritic polyester polymer and preparation method and application thereof | 清华大学深圳国际研究生院 | 2023-10-13 | — | — | CN | claimed |
| US-20260015313-A1 | AMINO ACID ACTIVE ESTER AND SALT THEREOF | PEPTIDREAM INC (JP) | 2026-01-15 | — | — | US | disclosed |
| EP-4534524-A1 | AMINO ACID ACTIVE ESTER AND SALT THEREOF | PeptiDream Inc. (JP) | 2025-04-09 | — | — | EP | disclosed |
| CN-116874803-A | Antibacterial dendritic polyester polymer and preparation method and application thereof | 清华大学深圳国际研究生院 | 2023-10-13 | — | — | CN | disclosed |
| US-20220411362-A1 | DITERPENOID COMPOUNDS THAT ACT ON PROTEIN KINASE C (PKC) | K-GEN THERAPEUTICS, INC. | 2022-12-29 | — | — | US | disclosed |
| WO-2017222083-A1 | NOVEL COMPOUNDS | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2017-12-28 | — | — | WO | disclosed |
| CN-103582644-B | Phthalazinone-Pyrrolopyrimidine Carboxamide Derivatives | 塔科达有限责任公司 | 2016-07-20 | — | — | CN | disclosed |
| US-20160152576-A9 | AKT PROTEIN KINASE INHIBITORS | ARRAY BIOPHARMA, INC. (US) | 2016-06-02 | — | — | US | disclosed |
| US-20160108049-A1 | Novel Phthalazinone-Pyrrolopyrimidinecarboxamide Derivatives | ASTRAZENECA AB (SE) | 2016-04-21 | — | — | US | disclosed |
| US-9273008-B2 | Dual-acting imidazole antihypertensive agents | THERAVANCE BIOPHARMA R&D IP, LLC (US) | 2016-03-01 | — | — | US | disclosed |
| EP-0869786-B1 | PHARMACEUTICAL COMPOUNDS | LILLY CO ELI (US) | 2003-03-05 | — | — | EP | disclosed |
| US-20020128185-A1 | Pharmaceutical compounds | HAWAII, UNIVERSITY OF | 2002-09-12 | — | — | US | disclosed |
| US-6376230-B1 | Stereoselective process for producing intermediates of cryptophycins | ELI LILLY AND COMPANY | 2002-04-23 | — | — | US | disclosed |
| EP-1127055-A2 | STEREOSELECTIVE PROCESS FOR PRODUCING CRYPTOPHYCINS | ELI LILLY AND COMPANY (US) | 2001-08-29 | — | — | EP | disclosed |
| EP-1078919-A1 | SYNTHESIS OF $g(a)-AMINO-$g(a)',$g(a)'-DIHALOKETONES AND PROCESS FOR THE PREPARATION OF $g(b)-AMINO ACID DERIVATIVES BY THE USE OF THE SAME | KANEKA CORPORATION (JP) | 2001-02-28 | — | — | EP | disclosed |
| WO-2000034252-A2 | PROCESS FOR THE PREPARATION OF CRYPTOPHYCIN DERIVATIVES | ELI LILLY AND COMPANY (US) | 2000-06-15 | — | — | WO | disclosed |
| WO-2000023429-A2 | STEREOSELECTIVE PROCESS FOR PRODUCING CRYPTOPHYCINS | ELI LILLY AND COMPANY (US) | 2000-04-27 | — | — | WO | disclosed |
| EP-0869786-A4 | PHARMACEUTICAL COMPOUNDS | LILLY CO ELI (US) | 1999-04-14 | — | — | EP | disclosed |
| EP-0869786-A1 | PHARMACEUTICAL COMPOUNDS | ELI LILLY AND COMPANY (US) | 1998-10-14 | — | — | EP | disclosed |
| WO-1997023211-A1 | PHARMACEUTICAL COMPOUNDS | ELI LILLY AND COMPANY (US) | 1997-07-03 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20260015313-A1 | AMINO ACID ACTIVE ESTER AND SALT THEREOF | NSUN3, BCAT1, SLC43A1 | ATM 4553/4885APP 4712/4885CTSS 4022/4885 |
| US-20020128185-A1 | Pharmaceutical compounds | XPO5, XPOT, XPO1 | ATM 2247/4885APP 4296/4885CTSS 1721/4885 |
| US-20220411362-A1 | DITERPENOID COMPOUNDS THAT ACT ON PROTEIN KINASE C (PKC) | PRKCA, PRKCH, PRKCB | ATM 570/4885APP 4745/4885CTSS 3848/4885 |
| US-20160152576-A9 | AKT PROTEIN KINASE INHIBITORS | AKT1, AKT2, AKT3 | ATM 150/4885APP 4101/4885CTSS 3033/4885 |
| US-20160108049-A1 | Novel Phthalazinone-Pyrrolopyrimidinecarboxamide Derivatives | PDE4A, PDE4B, PDE5A | ATM 3781/4885APP 3751/4885CTSS 1616/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.