Quinoline

Quinoline

SCHEMBL28579596

CCc1nc2ccccc2s1.c1ccc2ncccc2c1

nearest known ligand 0.53

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.53
UBE2T Q9NPD8 1/20 0.51
ASIC3 Q9UHC3 1/20 0.51
NPC1 O15118 8/20 0.51
RAB9A P51151 8/20 0.51
SMN1; SMN2 Q16637 7/20 0.49
L3MBTL1 Q9Y468 3/20 0.49
MAPK1 P28482 2/20 0.49
MAPT P10636 5/20 0.48
PKM P14618 1/20 0.48
GAA P10253 2/20 0.47
CYP1A2 P05177 1/20 0.46
CYP2C19 P33261 1/20 0.46
PDE10A Q9Y233 1/20 0.46
KDM4E B2RXH2 4/20 0.45
HSD17B10 Q99714 2/20 0.45
TSHR P16473 2/20 0.45
TP53 P04637 1/20 0.45
KMT2A Q03164 2/20 0.45
MEN1 O00255 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL322456 0.87 UBE2T (0.66) ALDH1A1UBE2TASIC3NPC1RAB9A
SCHEMBL30626888 0.87 UBE2T (0.66) ALDH1A1UBE2TASIC3NPC1RAB9A
Iodide SCHEMBL9450324 0.85 UBE2T (0.63) ALDH1A1UBE2TASIC3NPC1RAB9A
Bromide SCHEMBL3752068 0.85 UBE2T (0.63) ALDH1A1UBE2TASIC3NPC1RAB9A
Quinoline SCHEMBL27735288 0.84 DRD2 (0.52) ALDH1A1UBE2TASIC3NPC1RAB9A
Quinoline SCHEMBL28276042 0.80 ALDH1A1 (0.52) ALDH1A1NPC1RAB9ASMN1; SMN2L3MBTL1
Quinoline SCHEMBL27500224 0.79 ALDH1A1 (0.59) ALDH1A1NPC1RAB9ASMN1; SMN2L3MBTL1
Perchlorate SCHEMBL5072706 0.78 UBE2T (0.54) ALDH1A1UBE2TASIC3NPC1RAB9A
Quinoline SCHEMBL2535469 0.77 ALDH1A1 (0.81) ALDH1A1NPC1RAB9ASMN1; SMN2MAPT
Quinoline SCHEMBL27345803 0.76 ALDH1A1 (0.55) ALDH1A1NPC1RAB9ACYP1A2CYP2C19

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-113013459-B Implantable vital energy source power generation system with high biocompatibility 国家卫生健康委科学技术研究所 2022-08-30 CN disclosed
CN-113013459-A Implantable vital energy source power generation system with high biocompatibility 国家卫生健康委科学技术研究所 2021-06-22 CN disclosed