Known targets — ChEMBL curated mechanism
CACNA1ACACNA1BCACNA1CCACNA1DCACNA1ECACNA1FCACNA1GCACNA1HCACNA1ICACNA1SCACNA2D1CACNA2D2CACNA2D3CACNA2D4CACNB1CACNB2CACNB3CACNB4CACNG1CACNG2CACNG3CACNG4CACNG5CACNG6CACNG7CACNG8
The experimentally established mechanism targets of Phloroglucinol. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH5A1 | P51649 | 1/20 | 0.52 |
| ▸ | ABAT | P80404 | 1/20 | 0.52 |
| ▸ | LCK | P06239 | 2/20 | 0.50 |
| ▸ | BACE1 | P56817 | 1/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.46 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.46 |
| ▸ | RAB9A | P51151 | 2/20 | 0.46 |
| ▸ | CA12 | O43570 | 3/20 | 0.40 |
| ▸ | CA1 | P00915 | 3/20 | 0.40 |
| ▸ | CA2 | P00918 | 3/20 | 0.40 |
| ▸ | CA7 | P43166 | 3/20 | 0.40 |
| ▸ | CA9 | Q16790 | 3/20 | 0.40 |
| ▸ | CA14 | Q9ULX7 | 3/20 | 0.40 |
| ▸ | CA5A | P35218 | 3/20 | 0.40 |
| ▸ | CA3 | P07451 | 2/20 | 0.40 |
| ▸ | CA4 | P22748 | 2/20 | 0.40 |
| ▸ | CA6 | P23280 | 2/20 | 0.40 |
| ▸ | CA13 | Q8N1Q1 | 2/20 | 0.40 |
| ▸ | CA5B | Q9Y2D0 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9261197 | 0.94 | LCK (0.58) | ALDH5A1ABATLCKBACE1KDM4E | |
| SCHEMBL37131 | 0.94 | LCK (0.58) | ALDH5A1ABATLCKBACE1KDM4E | |
| SCHEMBL4575600 | 0.94 | ALDH5A1 (0.52) | ALDH5A1ABATLCKBACE1KDM4E | |
| Potassium SCHEMBL31540630 | 0.91 | LCK (0.55) | ALDH5A1ABATLCKBACE1KDM4E | |
| SCHEMBL308093 | 0.83 | ALDH1A1 (0.47) | ALDH5A1ABATKDM4EPTGS2RAB9A | |
| Benzaldehyde SCHEMBL29155416 | 0.80 | ALDH1A1 (0.64) | ALDH5A1ABATLCKKDM4EPTGS2 | |
| SCHEMBL27332599 | 0.78 | LCK (0.48) | ALDH5A1ABATLCKKDM4EPTGS2 | |
| Glycine SCHEMBL8218439 | 0.77 | GLRA1 (0.42) | ALDH5A1ABATLCKKDM4EPTGS2 | |
| SCHEMBL1619002 | 0.76 | ALDH1A1 (0.55) | ALDH5A1ABATLCKKDM4EPTGS2 | |
| SCHEMBL668005 | 0.76 | ALDH1A1 (0.46) | ALDH5A1ABATLCKKDM4EPTGS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112952198-B | Sulfur energy storage battery and method for improving rate capability and cycle stability of sulfur energy storage battery | 华中科技大学 | 2023-03-10 | — | — | CN | disclosed |
| CN-112952198-A | Sulfur energy storage battery and method for improving rate capability and cycle stability of sulfur energy storage battery | 华中科技大学 | 2021-06-11 | — | — | CN | disclosed |