SCHEMBL668005

SCHEMBL668005

O=Cc1cc(O)cc(Br)c1

nearest known ligand 0.46

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.46
ERN1 O75460 4/20 0.43
ALDH5A1 P51649 2/20 0.42
ABAT P80404 2/20 0.42
LCK P06239 1/20 0.40
KDM4E B2RXH2 1/20 0.38
PTGS2 P35354 1/20 0.38
RAB9A P51151 1/20 0.38
MAOA P21397 2/20 0.36
MAOB P27338 2/20 0.36
TDP1 Q9NUW8 2/20 0.35
AOX1 Q06278 1/20 0.35
TRIM24 O15164 1/20 0.35
HPGD P15428 1/20 0.35
TRIM33 Q9UPN9 1/20 0.35
CYP3A4 P08684 1/20 0.35
TSHR P16473 1/20 0.35
XDH P47989 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30753265 1.00 ALDH1A1 (0.46) ALDH1A1ERN1ALDH5A1ABATLCK
SCHEMBL4575600 0.82 ALDH5A1 (0.52) ALDH1A1ALDH5A1ABATLCKKDM4E
SCHEMBL37131 0.82 LCK (0.58) ALDH1A1ALDH5A1ABATLCKKDM4E
SCHEMBL9261197 0.82 LCK (0.58) ALDH1A1ALDH5A1ABATLCKKDM4E
SCHEMBL646947 0.82 ALDH1A1 (0.56) ALDH1A1ERN1ALDH5A1ABATKDM4E
SCHEMBL708554 0.82 ALDH1A1 (0.56) ALDH1A1ERN1ALDH5A1ABATKDM4E
Potassium SCHEMBL31540630 0.79 LCK (0.55) ALDH1A1ALDH5A1ABATLCKKDM4E
Phloroglucinol SCHEMBL28580013 0.76 ALDH5A1 (0.52) ALDH1A1ALDH5A1ABATLCKKDM4E
SCHEMBL16955787 0.76 LCK (0.40) ALDH1A1LCKKDM4EPTGS2RAB9A
SCHEMBL25180638 0.73 KDM4E (0.53) ALDH1A1LCKKDM4EPTGS2TDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 194 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0423010-B1 METHOD FOR THE PRODUCTION OF ALKOXYBENZALDEHYDES RHONE-POULENC CHIMIE (FR) 1993-09-29 EP claimed
EP-4565562-B1 PYRROLIDINE-2-CARBOXAMIDE DERIVATIVES AS PROSTAGLANDIN E2 RECEPTOR 4 (EP4) AGONISTS FOR THE TREATMENT OF GASTROINTESTINAL AND PULMONARY DISEASES NXERA PHARMA UK LTD (GB) 2026-05-27 EP disclosed
US-20260078094-A1 ANTI-VIRAL COMPOUNDS INFEX THERAPEUTICS LTD (GB) 2026-03-19 US disclosed
US-20260042745-A1 PYRROLIDINE-2-CARBOXAMIDE DERIVATIVES AS PROSTAGLANDIN E2 RECEPTOR 4 (EP4) AGONISTS FOR THE TREATMENT OF GASTROINTESTINAL AND PULMONARY DISEASES NXERA PHARMA UK LIMITED (GB) 2026-02-12 US disclosed
US-12492174-B2 Morpholine-3-carboxamide derivatives as prostaglandin E2 receptor 4 (EP4) agonists for the treatment of gastrointestinal and pulmonary diseases NXERA PHARMA UK LIMITED (GB) 2025-12-09 US disclosed
EP-4587425-A1 ANTI-VIRAL COMPOUNDS Infex Therapeutics Limited (GB) 2025-07-23 EP disclosed
US-20250179036-A1 MORPHOLINE-3-CARBOXAMIDE DERIVATIVES AS PROSTAGLANDIN E2 RECEPTOR 4 (EP4) AGONISTS FOR THE TREATMENT OF GASTROINTESTINAL AND PULMONARY DISEASES NXERA PHARMA UK LIMITED (GB) 2025-06-05 US disclosed
CN-119866328-A Antiviral compounds 英菲克斯治疗有限公司 2025-04-22 CN disclosed
CN-119855814-A Morpholine-3-carboxamide derivatives as prostaglandin E2 receptor 4 (EP 4) agonists for the treatment of gastrointestinal and pulmonary diseases 奈克斯拉制药英国有限公司 2025-04-18 CN disclosed
EP-4532491-A1 MORPHOLINE-3-CARBOXAMIDE DERIVATIVES AS PROSTAGLANDIN E2 RECEPTOR 4 (EP4) AGONISTS FOR THE TREATMENT OF GASTROINTESTINAL AND PULMONARY DISEASES Nxera Pharma UK Limited (GB) 2025-04-09 EP disclosed
EP-2091955-A1 ALKOXY COMPOUNDS FOR DISEASE TREATMENT Acucela, Inc. (US) 2009-08-26 EP disclosed
WO-2009045479-A1 ALKOXY COMPOUNDS FOR DISEASE TREATMENT ACUCELA INC. (US) 2009-04-09 WO disclosed
WO-2009045479-A1 ALKOXY COMPOUNDS FOR DISEASE TREATMENT ACUCELA INC. (US) 2009-04-09 WO disclosed
WO-2008141462-A9 NOVEL CASE OF RENIN INHIBITORS MERCK FROSST CANADA LTD (CA) 2009-01-08 WO disclosed
WO-2008141462-A1 NOVEL CASE OF RENIN INHIBITORS MERCK FROSST CANADA LTD. (CA) 2008-11-27 WO disclosed
WO-2008058387-A1 RENIN INHIBITORS MERCK FROSST CANADA LTD. (CA) 2008-05-22 WO disclosed
EP-1910272-A1 RENIN INHIBITORS Merck Frosst Canada Ltd. (CA) 2008-04-16 EP disclosed
WO-2007009250-A1 RENIN INHIBITORS MERCK FROSST CANADA LTD. (CA) 2007-01-25 WO disclosed
WO-2007009250-A1 RENIN INHIBITORS MERCK FROSST CANADA LTD. (CA) 2007-01-25 WO disclosed
WO-2005037756-A2 NOVEL METHODS FOR THE PREPARATION OF 4-[4-(4-METHOXYMETHOXY-4'-METHYL-BIPHENYL-2-YL)-BUT-3-ENE-(E)-1-YNYL]-BENZOIC ACID GALDERMA RESEARCH & DEVELOPMENT, S.N.C. (FR) 2005-04-28 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260042745-A1 PYRROLIDINE-2-CARBOXAMIDE DERIVATIVES AS PROSTAGLANDIN E2 RECEPTOR 4 (EP4) AGONISTS FOR THE TREATMENT OF GASTROINTESTINAL AND PULMONARY DISEASES PTGER4, PTGER1, PTGER2 ALDH1A1 1803/4885ERN1 2321/4885ALDH5A1 1839/4885
US-12492174-B2 Morpholine-3-carboxamide derivatives as prostaglandin E2 receptor 4 (EP4) agonists for the treatment of gastrointestinal and pulmonary diseases PTGER4, PTGER1, PTGER2 ALDH1A1 1720/4885ERN1 2687/4885ALDH5A1 949/4885
US-20260078094-A1 ANTI-VIRAL COMPOUNDS CBR1, CBR3, CPN1 ALDH1A1 3141/4885ERN1 164/4885ALDH5A1 4031/4885
US-20250179036-A1 MORPHOLINE-3-CARBOXAMIDE DERIVATIVES AS PROSTAGLANDIN E2 RECEPTOR 4 (EP4) AGONISTS FOR THE TREATMENT OF GASTROINTESTINAL AND PULMONARY DISEASES PTGER4, PTGER1, PTGER2 ALDH1A1 1720/4885ERN1 2687/4885ALDH5A1 949/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.